23 



larynx, and upper third of trachea, and also on the con- 

 junctiva, I am inclined to think that the percentage of 

 cases observed by me in these parts is probably above 

 the average, although Tokishige relates quite a number 

 of cases in which the mucous membranes were the 

 seat of the disease. 



Plates XIII, XIV, XV, and XVI show very clearly 

 the lesions as they were seen in some of those parts, 

 and I may here mention that in each case the diagnosis 

 was verified by microscopical examination, that of 

 Plate XIII being also tested with mallein gave no 

 reaction, nor were any lesions of glanders recognized in 

 the lungs of any of them. 



The lesions in the nose have been observed by 

 me both uni-lateral and bi-lateral, and a tendency for 

 them to become bi-lateral was noticed to prevail. 

 Some writers on the subject state that, in contrast to 

 glanders, the lesions are only found in the lower third 

 of the nasal chambers. I have noticed myself that 

 it is certainly commonest only in that portion, but have 

 ample proof to show that most extensive lesions of the 

 disease (unaccompanied by glanders) may occasionally 

 be found in all the nasal chambers, and that they may 

 also extend to the pharynx, larynx, and trachea. 



Nocard and Leclainche state that the lesions in the 

 nose are almost always bi-lateral, that they may extend 

 to the pharynx, larynx, and trachea, and, in exceptional 

 cases, to the large bronchial tubes, I might here mention 

 that in addition to a few characteristic cutaneous cases 

 of the disease observed in North China in 1900 and 

 1 901 amongst Chinese ponies and mules, I also saw in 

 addition to marked glanders cases, several other cases ot 

 so-called glanders, showing most extensive lesions on the 

 nasal mucous membrane very much resembling glanders, 

 but there was no submaxillary glandular enlargement ; 



