132 



THE FARMERS' REGISTER. 



extensively known, as we have lately i=een amply 

 proved and iilusiraied at the " Ecole Veterinaire" 

 o( Alfbit, near Paris. Presiinning that foinc in- 

 formation on these suhjecis would prove iiselid as 

 well as interesting to ihe readers oi' " The Sport- 

 ing Magazine," we propose in the tbllowiug 

 ariicles to lay helbre ihen> a succinct view of liicis 

 and experitnents relating to the disease both in 

 man and in the horse, and, by inlerlardiiig the 

 subject wihsonie incidental matter, we hope lo 

 divest it of liie dryness of detail — in a word, to 

 blend together, as lar as lies in our power, the 

 uiile et dulce. 



M. Wnldinger, veterinary surg' on at V^ienna, 

 was the first to direct attention to the liability ol 

 man to be atfi'cted with glanders. He stales 

 "that the greatest precauiion is necessary in 

 going about glandered horses, or those that died 

 from glanders or farcy, as the severest injury and 

 even death olten arise from inoculation.'' 



iVl. Lorin piiblishcil some observations shortly 

 after on the same subject, in which he men'ions 

 that a groom had his fingers affected with inflam- 

 mation in consef]uence of o[)eratinir on a farcied 

 horse: tumors precisely similar to those observed 

 in the horse were soon developed in this man's 

 limbs; they were cut out, anil he was ultimately 

 cured by filling the wounds with small pieces ol 

 lint or cotton steeped in turpentine. 



Sidon, another veterinary surgeon, published 

 a paper about the same lime, in which he staled 

 that glanders was transmissible fiom the horse 

 to man, causing the worst kind of ulcers; and 

 mentions an instance where a horse took ilie dis- 

 ease from a farrier who had a glandered sore on 

 his hand, which came in coritaci with the animal 

 while he was giving it a ball — boih ilied of the 

 disease. 



We might multiply instances of a similar bear- 

 ing from Ibreign sources, but these will suffice. 



We shall now briefly narrate lads which came 

 under our own immediate observation. 



A groom named Frost slept in a stable at Paris 

 occupied by a glandered horse. Some days after 

 the death of the animal, Prost was attacked wiili 

 the same disease, whicli was characterized by 

 pustular and gangrenous sores over the body, in 

 the nose and thioat. below the ears, on the gfans, 

 and on the leet. He died on the 12 h oi' lust 

 February. On the evening of Prost's death, a 

 small quantity of mailer was cofected on watch 

 glasses from the gangrenous eorcs beneath the 

 ear, on the lore-arm, and from the back and 

 shoulder. A li)undered mare was iinmediately 

 inoculated liy a veterinary surgeon with ihedifle- 

 rent portions of matter. 



First, at ihe ri^bt ndstril he inoculated ihe mat- 

 ter by ihree punctures, of which two were within 

 the nostril and one external: the two first punc- 

 tures gave rise to a weeping of blood ; but the 

 other produced scarcely any. Second, on the 

 wiiile pan or conjunction of ihe riiiht eye he 

 applied a small ipianiiiy of ihe matter.^ Third, at 

 the imernal and upper part of the right buttock 

 he inoculated the mailer by three punctures. 

 Fourth, at the internal part of the right artnpit he 

 also inserted the matter by three punctures. The 

 left s'de of the animal was inoculated in a similar 

 manner. 



MM. Leblanc, Dupuy, Vigla, and Desir, gen- 

 iJemen belonging to the Veterinrjry t'ollege, were 



present at the inoculation of the horse. A diary 

 of the diHerenl resuhs was kept. 



On the ISih and 14ih no appreciable change 

 could be observed in the state of ihe parts inocu- 

 lated. On ihe evening of the 15:h, at 7 o'clock, 

 slight circular and circumscrilied redness and 

 swelling were observable round the punctures on 

 the right buttock ; at the centre o( the swelling a 

 depression was seen corresponding to each punc- 

 ture : there was a painful swelling in the region of 

 ;he leli buttock where the f;unctures had been 

 made. The circumference of the wings of the 

 left nostril were a little tumefied ; there ooz^d 

 a small quantiiy of [)ale colored fluid from the 

 internal wing; there was also effused a small 

 quantity of serum from the internal wing of the 

 right nostril ; but the circumference of the punc- 

 tures was not so swollen. The pulse was natural, 

 fortv-eiijht pulsations in a minute. 



On the 16th, at seven in the morning, no changft 

 was observed. In ihe evenins the symptoms of 

 inoculation were beginning to be marked. 



17ih. — At eight in the morning the tumefaction 

 of the puni'tures was increased ; the tumors are 

 more hot, harder, and more painful. On the side 

 of the upper lip, near the angle of the mouth, 

 two elevated hands were observed about an inch 

 in thickness, elongated, irregular, and slightly 

 painful. The left eyelids are greatly swollen, and 

 the conjunction red. The air expired by the ani- 

 mal has a disagreeable odor, and the nostrils are 

 snveared with fluid. The pulse still natural; the 

 animal eats well. 



18th. — At seven in the morning: the nodulate<l 

 tumors of the right buttock are united by a band 

 of lesser ones, very b.ot and very painfiil : there 

 flows from the nostrils a fluid more colored and 

 more abundant than was yet observed. Now 

 mark llie ropid advance of" the difease. 



19ih. — The circumference of the pimctures in 

 the nostrils appears niore tumefied, especially on 

 the leftside; the respiration is more difficult ; all 

 the tumefied parts are verv painful ; the animal 

 eats very little, iind that little vviih difiiculiy. 



20lh, morning. — Exasperation of ail the symp- 

 toms ; ihe banil on ihe upper lip is greatly in- 

 creased, and very painfiil ; all ihe tumors are cir- 

 cumscrdu'd. and terminate abruptly, precisely like 

 those peculiar \o farcy ; the animal with much 

 difficulty is enabled to open her mouih to lake 

 Ibod. 



21st. — The symptoms of ir'jection were still 

 more marked, and the local pain greatly increas- 

 ed. The disease still proceeded steadily in its 

 course for some days; and on the twenty-first 

 day from Ihe period of inoculation, the nnfbrfunato 

 animal was kilie '. after having presented all the 

 characieristirs of glanders and farcy. After 

 death ihe diseased portions of the horse were 

 excised, and on careful examination were fi>und 

 to be exacllv Ihe same as those commonly found 

 in glandered animals. 



Several useful inlerences may be drawn from 

 the foregoing detail. In the first place, it proves 

 beyond a doubt that it was glanders the man died 

 of, as a horse otherwise healthy was impiegnaied 

 with that disease by the inoculation of matter 

 taken from Prost alter death. Every one knows 

 that the horse usually lakes ihe disease, without 

 being inoculated, by cnntogion, as it is called ; but 

 until Ihe foregoing inquiry was instituted, it was 



