25 



same. In some instances they were more marked and appeared more 

 quickly llian in others, but the course did not differ greatly except as 

 regards time. 



As determined by examination and inquiry they were as follows : 

 A disposition to leave the other animals in the herd, wandering about 

 the pasture, jumping fences and running, loss of appetite, cessation 

 of lumination, gradual and rapid suppression of secretion of milk, 

 grating of the teeth with champing of the jaws : frequent attacks of 

 bellowing, following in quick succession, being at first loud, clear 

 and distinct, gradually growing weaker with a tendency to become 

 oontinuous and higher in pitch, but less distinct. The temperature was 

 normal and there was but slight alteration of the pulse. In an adult 

 cow that had been sick six or eight hours it was about forty-eight per 

 minute and nearly of normal strength. In a ten months old calf that 

 had been suffering for two days and showed well marked symptoms 

 it was found to be forty-eight with the temperature normal. 



After an attack of a few hours' duration frequeut stepping with tlie 

 hind logs with an incessant whisking of the tail would be seen. 

 Trembling of the muscles of the flank and hips invariably appeared, 

 and as the disease developed this increased in severity and extent, 

 including the muscles of the shoulder and anterior extremities. At 

 the outset there appeared to be a peculiar expression about the face, 

 due to the position in which the head and ears were carried and to the 

 condition of the eyes. The neck was extended, with the head car- 

 ried somewhat above the natural position of an animal when stand- 

 ing idle. The ears were erect. The eyes widely opened, with the 

 pupils dilated. To every appearance the animals seemed to be some- 

 what surprised and intensely interested in some distant object. 



The peculiar and most prominent symptom and one of the first to 

 appear Avas tenesmus. The cows would stand from the first with tails 

 slightly elevated and the muscles of the anus relaxed. 



At frequent intervals and at any time when made to move, the tails 

 would be still more raised and a slight effort made to expel faeces. 

 When successful in the attempt, only a small quantity would be 

 evacuated. This in most cases was normal in consistency and 

 appearance with perhaps a slight increase in the amount of mucus 

 present. 



The functions of the urinary organs were not sufficiently interfered 

 ■with to attract attention. 



While all of the animals refused food, thirst was a prominent 



