20 



symptom and all in the first stages partook freely of water. In a 

 single instance, the owner inCormed me, that one cow when first taken 

 ill stood for tlie greater part of one day at tlie trough, frequently 

 taking a few swallows and when unable to swallow endeavoring to 

 lap the water. This she continued to do until a few hours before 

 being slaughtered. 



As the disease developed, the symptoms became more and more 

 urgent, varying, however, in different animals. In some, they indi- 

 cated the development of more intense cerebral irritation, producing 

 a condition mnrked by great uneasiness and excitement ; while in 

 others, the symptoms indicated mental depression with a tendency 

 toward paralysis. 



In those cases where the animals were inclined to become more 

 excited, the head would be carried higher, the eyes became more 

 prominent, the bellowing louder and more frequent, appearing how- 

 ever in paroxysms conlinuing with some for hours with short inter- 

 vals of cessation. The stepping with the hind logs was followed by 

 occasional kicking at the belly and a reckless kiclxing backward as if 

 to strike some object. There was pawing with the fore-feet and in 

 some goring of the earth. 



The movements were partially controlled but were unnatural, as 

 was determined b}' driving two of the affected creatures that had been 

 sick for two days over a narrow ditch, partially filled with water. 

 They appeared to be conscious of the position of the ditch and con- 

 trolled the action of the muscles sufficiently well to be able to cross 

 without stepping in or falling, but it was approached cautiously with 

 an appearance that indicated an uncertainty, and when the feet were 

 raised to step across they were raised to a much greater height and 

 with more of a feeling motion than was natural in such cnses. 



The general actions of the animals in these efforts might very 

 appropriately be compared to the action of a man in his stocking 

 feet feeling his way about in a dark room in which there were num- 

 erous chairs and other objects, or to that of a blind horse feeling his 

 way along over rough and uneven places. The same sj'mptom was 

 exhibited by a ten months' old calf which had been sick two days, 

 when made to step over a log eight or ten inches in di.imeter. 



The cows were driven through a pool of water which was fifty or 

 seventy-five feet across and eighteen inches or two feet in depth at 

 its deepest part. They showed no hesitation or fear when made to 

 enter the water and were rather inclined to remain standing in it. 



