At times they would attempt to drink, but so far as noticed little or 

 no water was swallowed. No spasm or excitement was produced 

 when an attempt was made. 



Of two of Mr. Cheever's cows, the brindle and red ones (Nos. 3 

 and 4 of the table) both of which were taken sick on June sixth, he 

 informs me under date of June fourteenth that the red cow died on 

 Saturday, June ninth, about eleven o'clock a.m. and the brindle one 

 Sunday, June tenth, at five o'clock p. m. He further states that on 

 Saturday, before death, the red cow was very uneasy, and as long as 

 she lived would follow and hook at the hens, and that there was some 

 saliva about the mouth. Two hours after her death he opened her, 

 but could find nothing abnormal, except that the blood was very 

 black and thick. The brindle cow appeared better on Saturday until 

 night, when she became restless and remained so while she lived. 

 On Sunday, the day of her death, she caught sight of a dog through 

 the cracks between the boards of the stable, and became very much 

 excited, frothing at the mouth. 



The tenesmus which was a prominent symptom with all in the 

 first stages became more marked as the disease developed, and with 

 all of the animals became the most prominent and characteristic 

 symptom. Instead of standing with the tail slightly elevated 

 and the muscles of the anus relaxed, they soon assumed a position 

 with the back arched, the tail well elevated, the sphincter muscles so 

 relaxed that the anus remained constantly open, and instead of an 

 occasional slight eifort to defecate there was the most pronounced 

 jerky, spasmodic straining that could possibly exist. While this 

 was almost constant, it was more pronounced, however, at times, and 

 seemed to occur paroxysmally. During the paroxysms, the strains 

 were at intervals of about ten seconds and were quite characteristic, 

 being unlike corresponding efforts noticed in any other diseases with 

 which the writer is acquainted. The effort was distinctly jerky and 

 convulsive and was produced wholly by a spasmodic contraction of 

 the abdominal muscles, instead of resulting from a tonic or progres- 

 sive contraction. With each convulsive strain there was enlarge- 

 ment of the anus and expulsion per rectum of a small quantity of 

 frothy mucus. 



On account of the relaxed condition of the sphincter muscles and 

 the expansion of the abdomen by relaxation of the abdominal mus- 

 cles, large quantities of air were drawn into the rectum at the expir- 

 ation of each strain ; this became mixed with the mucus secreted,. 



