SALICYLIC ACID AND SALICYLATES. 489 



day of the first preservative subperiod the temperature was slightly 

 above the normal, but no other symptoms of abnormality were observed. 

 This increase in temperature also continued during the 31st, and on 

 November 1 the temperature was again normal and the weight had 

 increased to 68.35 kilograms, fallowed by a fall on November 2 to 

 67.85 kilograms. The average weight for the first preservative sub- 

 period was 68.01 kilograms. 



The second preservative subperiod began on November 3 with normal 

 temperature and a weight of 68.05 kilograms. On the 5th of Novem- 

 ber No. 2 was reported as feeling well with the exception of a slight 

 headache. There was also a slight depression of temperature after 

 dinner in this case instead of before. On the 7th of November No. 2 

 described himself as "hungry as a bear." -Temperature and respira- 

 tion, however, remained normal. The weight of the body had fallen 

 on November 7 to 67.60 kilograms, the average weight for this sub- 

 period being 67.84, a slight decrease as compared with the average for 

 the preceding subperiod. 



The third preservative subperiod began on November 8 with all 

 symptoms normal. On the 9th No. 2 described himself as still hungry, 

 and on the 10th as feeling all right. On the llth he was normal, and 

 the hungry feeling had disappeared. The average weight was 67.80, 

 theoretically a very slight decrease. 



The fourth preservative subperiod began on the 13th of November 

 with no unfavorable symptoms. On November 14 No. 2 described 

 himself as feeling a little feverish and as having a bad headache in 

 the morning. On the 15th of November the headache continued all 

 day, but the subject was not ill. The headache disappeared on the 

 16th. This subperiod closed on the following day with an average 

 weight of 67.65 kilograms, the average decrease continuing. 



On the 18th, the first day of the fifth preservative subperiod, there 

 were decided pains in the stomach, and the temperature fluctuated 

 somewhat, but there were no marked symptoms of fever. The weight 

 on this day was 67.63 kilograms. The condition of No. 2 remained 

 normal from this time until the beginning of the sixth preservative 

 subperiod, on November 23, when he had nausea during the whole 

 afternoon. After dinner on the 24th he returned to the dining room 

 after a short absence complaining of very severe burning pains in the 

 stomach, and was evidently quite ill and in considerable distress. 

 After meals on November- 25 there were burning sensations in the 

 stomach which lasted fof a greater or less length of time, and the 

 weight decreased to 67.11 kilograms. On the, 26th the patient was 

 feeling better, could eat more, arid the appetite was fairly good. On 

 the 27th extreme sensitiveness in the stomach was manifested, and 

 there was a slight increase of temperature at the dinner hour. The 

 7656 No. 84, pt 206 2 



