SALICYLIC ACID AND SALICYLATES. 493 



unusual feeling of hunger, and with a weight of 60.51 kilograms. 

 There was an increase in the average weight to 60.62 kilograms. 



The fourth preservative subperiod began with a good appetite and 

 no unfavorable symptoms. At the end of the period there was a 

 slight increase in weight, namely, to 60.90 kilograms, and the average 

 weight also increased to 60.85 kilograms. 



The fifth preservative subperiod began with a good physical condi- 

 tion, normal in every respect. At the close of this period the normal 

 conditions were still maintained, with good appetite but not excessive 

 hunger, and the weight had risen to 61 kilograms, though the average 

 weight slightly decreased, being 60.81 kilograms. 



During the sixth preservative subperiod the patient complained of 

 a slight headache but still had a fairly good appetite, though not so 

 keen as during the earlier preservative subperiods. The average 

 weight for the entire preservative period was 60.67 kilograms, a 

 slight decrease as compared with the fore period average. 



At the close of the first after subperiod normal conditions still 

 continued, but the weight had fallen to 60.35 kilograms, though 

 showing an average of 60.42 kilograms. The second after subperiod 

 began with normal conditions, which continued unchanged to the end 

 of the period, w^hen the pulse and temperature were normal, and the 

 weight was 60.38 kilograms and the average 60.43 kilograms. The 

 average weight for the entire after period was 60.43 kilograms, 

 showing a continued loss in weight throughout the experiment. 



No. 5.G. E. C. 



No. 5 began the fore period in good physical condition, with 

 temperature and pulse slightly below the normal. His weight was 

 59.43 kilograms. No unfavorable symptoms were developed during 

 the fore period, the physical condition of the subject remaining 

 practically unchanged. During the whole observation there seemed 

 to be a slight normal depression of the temperature, which, however, 

 was not due to any unusual cause. At the end of the fore period 

 No. 5 was in excellent physical condition, with temperature slightly 

 below the normal. The weight had risen to 59.94 kilograms, the 

 average weight for the entire fore period being 59.76 kilograms. 



The first preservative subperiod was passed without any unusual 

 symptoms, except the continued slight depression of the temperature 

 until November 2, when a slight headache was developed which con- 

 tinued during the whole dky . The second preservative subperiod passed 

 without any unusual phenomena until the 7th of November, when a 

 remarkably strong appetite persisted after the last meal of the day. 

 The weight of the subject on this date was 59.83 kilograms, the average 

 weight for the subperiod being 60.07 kilograms. The third preserva- 

 tive subperiod passed without incident until November 10, when the 



