SALICYLIC ACID AND SALICYLATES. 503 



ATo. IZ.^R. B. R. 



No. 12 was one of the very best men of the class. His weight at 

 the beginning of the fore period was 69.50 kilograms; his tempera- 

 ture and pulse were normal. No unfavorable symptoms of any 

 description were developed during the entire fore period and his 

 average weight was 69.70 kilograms. 



No. 12 entered the preservative period in excellent condition, weigh- 

 ing 0>9.80 kilograms, and with normal pulse and temperature. No 

 unfavorable symptoms were recorded during the first preservative 

 subperiod. A good deal of mental work was required on November 

 3, probably incident to his studies. The amount of exercise taken on 

 November 5 was less than usual, No. 12 having experienced a feeling 

 of drowsiness on that day with a sensation of fullness in the head and 

 a slight headache which persisted during the entire day. He was 

 nervous during the night of the 5th, but there* was some improvement 

 in his feelings during the 6th. On this date also there were symp- 

 toms of a slight cold in the head and the feeling of fullness in the head 

 continued. There was also a loss of appetite, and the urine discharged 

 during the day was more cloudy than usual. The loss of appetite 

 continued during the following day, but otherwise No. 12 was feeling 

 very much better. 



The third preservative subperiod began with a severe headache which 

 lasted all day, but there was some improvement in the appetite. He 

 complained of feeling very hungry at dinner time. The headache 

 and other unfavorable symptoms had passed away on the 9th, and the 

 feeling of hunger was increased. On the 10th, however, the appetite 

 failed again partially, and symptoms of a bad cold were manifested, 

 but without any marked increase in temperature or pulsation. 



No. 12 was better on November 11, but on the following day he was 

 not so well. He had a feeling of fatigue, although he had not taken 

 any more than the usual amount of exercise, and the symptoms of 

 hunger persisted. 



The fourth preservative subperiod was marked by a slight loss of 

 appetite and a headache which continued during the day. Otherwise 

 No. 12 was feeling very well. On the 14th he was extremely nervous, 

 and had not slept well during the previous night. The headache and 

 a sense of dryness in the mouth and throat continued throughout the 

 day, and the headache persisted during the following day with a loss 

 of appetite. The headache^ontinued during the day of November 16, 

 but otherwise the symptoms were more favorable and the subject 

 improved. The unfavorable symptoms had passed away on the 17th, 

 and a feeling of hunger was manifested. 



The fifth preservative subperiod found No., 12 in the possession of 

 a good appetite and without any indisposition of any kind. The rest- 

 less condition, however, returned on the night of the 18th and lasted 



