SALICYLIC ACID AND SALIC YLATES. 585 



the first fore subperiod, in which some abnormality is shown to exist, 

 and this influence, as in the first instance, is continued during the 

 after period. 



No. 3. 



Owing to illness No. 3 had only a partial fore period, and this was 

 taken at the beginning of the preservative period for the other men, 

 extending from October 29 to November 2, inclusive. During this 

 period the total quantity of nitrogen exhibited in the food is 72.58 

 grams, with an average of 14.52 grams per day; 7.38 per cent of the 

 nitrogen exhibited is excreted in the feces and 87.06 per cent in the 

 urine. The daily nitrogen balance is 0.81 grams. During the pre- 

 servative period, extending from November 3 to 27, inclusive, five days 

 less than in the other cases, the . total quantity of nitrogen exhibited 

 in the food is 369.08 grams, an equivalent of 14.76 grams per day. 

 The percentage of nitrogen excreted in the feces is 7.62 and in the 

 urine 76.20. The excretion of nitrogen in this case is strongly inhibited 

 and the nitrogen balance becomes very largely positive, reaching the 

 very large amount of 2.39 grams per day. The after period in the 

 case of No. 3 was again interrupted by illness, and covers only five 

 days, therefore it is not comparable. It is evident that the data in 

 the case of No. 3 are wholly useless for comparison by reason of 

 interruption of the observations by illness both at the beginning and 

 close of the investigations. . 



No. 4- 



During the fore period the quantity of nitrogen exhibited in the 

 food of No. 4 is 157.10 grams, equivalent to 15.71 grams per day. 

 Of this quantity, 6.86 per cent is excreted in the feces and 92.76 per 

 cent in the urine. The nitrogen balance is positive, but of very small 

 magnitude, amounting to 0.06 gram per day. During the preserva- 

 tive period the total quantity of nitrogen exhibited in the food is 

 468.11 grams, amounting to 15.60 grams per day. Of this quantity, 

 6.75 per cent is excreted in the feces and 90.42 per cent in the urine. 

 The nitrogen balance has been considerably increased in magnitude 

 and remains positive, amounting to 0.44 gram per day. During the 

 after period the amount of nitrogen exhibited in the food is 157.79 

 grams, equivalent to 15.78 grams per day. Of this quantity, 6.43 per 

 cent is excreted in the feces and 92.83 per cent in the urine. The 

 nitrogen balance remains positive, but is diminished in magnitude, 

 amounting to only 0.12 gram per day. The data in this case are in 

 general contrary to those of cases 1 and 2. The indications here are 

 that the action of the preservative serves to inhibit to a certain extent 

 the excretion of the nitrogen, thus increasing the magnitude of the 

 positive balance. 



7656 No. 84, pt 206 8 



