SALICYLIC ACID AND SALICYLATES. 605 



day, are found in the feces, and 21.686 grams, equivalent to 2.169 

 grams per day, -in the urine. The percentage of phosphoric acid 

 excreted in the feces is 30.85 and in the urine 58.55. The phosphoric 

 acid balance is positive, amounting to 0.393 gram per day. 



The to.tal quantity of phosphoric acid exhibited in the food during 

 the preservative period is 115.833 grams, equivalent to 3.861 grams 

 per day. The quantities in the various subperiods are quite constant, 

 as will be seen by inspection of the table. Of the total quantity exhib- 

 ited 30.921 grams are excreted in the feces, equivalent to 1.031 grams 

 per day, and 70.508 grams in the urine, equivalent to 2.35 grams per 

 day. Of the phosphoric acid exhibited in the food 26.69 per cent is 

 excreted in the feces and 60.87 per cent in the urine. The phosphoric 

 acid balance remains positive, and amounts to 0.48 gram per day. 

 During the after period the quantity of phosphoric acid exhibited in 

 the food is 37.551 grams, equivalent to 3.755 grams per day. Of this 

 amount there are excreted in the feces 18.39 grams, equivalent to 1.839 

 grams per day," and in the urine 21.342 grams, equivalent to 2.134 

 grams per day. Of the total phosphoric acid in the food 48. 97 per 

 cent is excreted in the feces and 56.83 per cent in the urine. This pro- 

 duces a negative phosphoric acid balance for the after period, amount- 

 ing to 0.218 gram per day. 



The data in the case of No. 1 show a slight increase in the magni- 

 tude of the balance during the preservative period and a marked 

 change, resulting in a negative balance, in the after period. This 

 remarkable increase in the excretion of phosporic acid in the after 

 period is entirely nonmetabolized phosphoric acid, the percentage 

 excreted being almost twice as great as in the preservative period, 

 while the quantity of metabolized phosphoric acid excreted is slightly 

 decreased in the after period. In this instance, therefore, it appears 

 that the withdrawal of the salicylic acid caused a very decided inter- 

 ruption of the digestion and absorption of the phosphoric acid in the 



intestinal canal. 



No. 2. 



The total quantity of phosphoric acid consumed by No. 2 during 

 the fore period is 43.005 grams, equivalent to 4.30 grams per day. 

 Of this quantity 14.101 grains appear in the feces, equivalent to 1.41 

 grams per day, and 30.292 grams appear in the urine, equivalent to 

 3.029 grams per day. The percentage of phosphoric acid eliminated 

 in the feces is 32.79 and in tjie urine 70.44, causing a negative balance 

 the magnitude of which is 0.139 gram per day. During the fore 

 period the quantity of phosphoric acid excreted was slightly greater 

 than that consumed. 



a The weight of the dry feces is 52 grams in the after period, while in the fore 

 period it is 41 grams and in the preservative period 35 grams. The increase in phos- 

 phoric acid excreted thus appears to be due to the increased fecal excretion. 



