674 



Cancer Research 



Tabu 8: Saicoha (UacUMificd) 



Specie* 

 Minnow Phoxinus lants 

 Goldfish Carassius auratus 

 Goldfish Carassius auratus 

 Pike Esox lucius 

 Brook trout Salvtlinus foHtinalis 

 Chub Idus idus 

 Minnow Phoxinus latns 

 Crucisn carp Carassius carassius 

 "LeNes" Chondrostoma nasus 

 Flounder PseUa maeolita 

 Scorpion fish Scorpaena parens 

 Pike Esox lucius 

 Danubian trout Uucko kucho 

 Codfish PoUackius virens 

 Ray Raja macrorkynckus 

 Eel AnguiUa vulgaris 

 Codfish Gadus munkua 

 Plaice PUuronectts plalessa 

 Codfish Gadus morkua 

 Croaker Pogonias ckromis 

 Conger eel Conger conger 

 Codfish species not given 

 Dog salmon Oncorkynckus kela 

 Haddock Mdanogrammus aeglifinus 

 Goldfish Carassius auratus 

 Goldfish Carassius auratus 

 Codfish Gadus morkua 

 Ling molva molva 

 Turbot Rkombus maximus 

 Herring Clupea karengus 

 Eel AnguiUa vulgaris (2) 

 Goldfish Carassius auratus 

 Rainbow trout Salmo gairdnerii (2) 

 Codfish PoUackius virens 

 Codfish PoUackius virens 

 Halibut Bippoglossus kippoglossus 

 Croaker Micropogon opercularis (2) 

 Codfish Gadus morkua 

 Codfish Gadus morkua 

 Turbot Rkombus maximus 

 Goldfish Carassius auratus 

 Dog salmon Oncorkynckus keta 

 Dog salmon Oncorkynckus keta 

 Hamp*back salmon Oncorkynckus gorbuscka 

 Coalfish Tktragra ckalcogramma 

 Coalfish Tkeragra ckalcogramma 

 Japanese bass Lateolabrax japonicus 

 Japanese bass Lateolabrax japonicus 

 Kfatlgo SiUago japonica 

 Gnmard Lepidopirigla aiata 

 Codfish Gadus morkua 

 Goldfish Carassius auralus (5) 

 Swordtail Xipkopkorus kcUerii (17) 

 Goldfish Carassius auratus (30) 



Site 

 Corium of skin 

 Dorsal fin 

 Not given 

 Trunk muscle 

 Trunk muscle 

 Trunk muscles 

 Trunk muscle 

 Testicle 



Muscles of back 

 Subcutaneous (multiple) 

 Subcutaneous 

 Kidney 

 Liver 

 Skin 

 Fin ray 

 Mesentery 

 Subcutaneous 

 Subcutaneous 

 Trunk muscle 

 Subcutaneous 

 Subcutaneous 

 Mouth 

 Rody wall 

 Subcutaneous 

 Subcutaneous 

 Subcutaneous 

 Subcutaneous 

 Subcutaneous 

 Subcutaneous 

 Testis 

 Peritoneum 

 Subcutaneous 

 Not given 

 Subcutaneous 

 Mandible 

 Body wall 

 Subcutaneous 

 Subcutaneous 

 Ovary 

 Body wall 

 Subcutaneous 

 Body wall 

 Body wall 

 Body wall 

 Body wall 

 Subcutaneous 

 Subcutaneous 

 Pharynx 

 Base of head 

 Left body wall 

 Body wall 

 Subcutaneous 

 Retrobulbar 

 Subcutaneous 



Author 

 Bugnion, 1875 

 Bland-Sutton, 1885 

 Semmer, 1888 

 Ohimacber, 1898 

 Plehn, 1906 

 Plehn, 1906 

 Plehn, 1906 

 Plehn, 1906 

 Plehn, 1906 

 Schroeders, 1908 

 Schroeders, 1908 

 Plehn, 1909 

 Plehn, 1909 

 Fiebiger, 1912 

 Drew, 1912 

 Wolff, 1912 

 Johnstone, 1912 

 Drew, 1912 

 Johnstone, 1915 

 Beatti, 1916 

 Johnstone, 1920 

 Johnstone, 1920 

 Kazama, 1922 

 Johnstone, 1922 

 Schamberg & Luck£, 1922 

 Johnstone, 1923 

 Johnstone, 1923 

 Johnstone, 1923 

 Johnstone, 1923 

 Johnstone, 1924 

 Plehn, 1924 

 Roffo, 1924 

 Leger, 1925 

 Johnstone, 1926 

 Johnstone, 1926 

 Johnstone, 1926 

 Roffo, 1926 

 Thomas, 1927b 

 Thomas, 1927b 

 Johnstone, 1927 

 Dominguez, 1928 

 Takahashi, 1929 

 Takahasbi, 1929 

 Takahashi, 1929 

 Takahashi, 1929 

 Takahashi, 1929 

 Takahashi, 1929 

 Takahashi, 1929 

 Takahashi, 1929 

 Takahasbi, 1929 

 Williams, 1931 



Montpellier & Dieuzeide, 1932 

 Jahnel, 1939 

 Luck6, Schlumberger & 

 Breedis. 1948 



One of the more malignant growths was success- 

 fully transplanted to the anterior chamber of the 

 eye of a tumor-bearing fish; all other attempts at 

 tran^lantation were unsuccessful. 



A possible hereditary sarcoma has been reported 

 by Jahnel (80). A retrobulbar tumor appeared in 

 each of four sibling tropical aquarium fish, known 

 •8 swordtaib, Xipkopkorus kelierii. Seventeen other 



siblings were traced, 9 of which developed tumors 

 in one or both orbits. Histologically the tumors 

 were identical, consisting of small round or spindle- 

 shaped cells with large vesicular nuclei; interstitial 

 tissue was almost absent. The tumor was markedly 

 invasive, infiltrated the orbital muscles and even 

 penetrated the skull. Mitotic figures were numerous. 

 In one animal a large tumor was present in the left 



