Schlumberger and Lucki — Tumors m Fishes 



675 



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atUched to the parietal peritoneum of a herring Clupca 

 karengus. It was fused with testis ftod «a» compoecd 

 of vesicular neoplastic cells. (Lymphosarcoma ?) 



Plehn, 1924: In each of two eels AngtaUa vuigom 

 there was a firm connective tissue tumor that arose in 

 the peritoneum and greaUy distended the abdomen. The 

 author gives no details but considers the tumors to be 

 fibrosarcomas. 



Lbgek, 1925: In discussing thyroid tumors in trout 

 the author mentions 2 fibrosarcomas in rainbow trout 

 SaJmo gairdnerii. They were red in color and very 

 vascular. No further details were given. 



Johnstone, 1926: On the top of the head of an 

 emaciated codfish PoUachhis virens was a tumor that 

 measured 2 inches in diameter. On section the lesion 

 was soft and necrotic. No histologic studies were made, 

 but the lesion was listed by the author as a sarcoma. 



Johnstone, 1926: A codfish PoUachius virens bore 

 a spherical tumor 8 cm. in diameter, on the anterior 

 median aspect of the mandible. The tumor extended 

 into the soft tissues of the mouth. Histologically it 

 consisted of neoplastic connective tissue cells. 



Johnstone, 1926: A superficial ulcer, measuring 8 

 z 5 inches and with raised edges, was observed on the 

 trunk surface of a halibut Hippoglossus hippoglossus. 

 Hie lesion was an ulcerated tumor that had deeply in- 

 filtrated the underlying muscle. Microscopic examina- 

 tion revealed that it was composed of loosely arranged 

 spindle celh. 



Rorro, 1926: Each of two croakers Micropogon 

 opercularis bore a tumor. In one a nodular ulcerated 

 mass 2 cm. in diameter was found at the junction of the 

 head and thorax; in the other a similar mass was pres- 

 ent at the base of the tail. Histologically each was a 

 spindle cell sarcoma. 



Thomas, 1927 b: A subcutaneous tumor the size of 

 a hen's egg was found in the trunk of each of 3 codfish 

 Gcdus morhua. Several areas of necrosis were present ; 

 the cells were large and fusiform, arranged in bands and 

 whorls that resembled the uterine fibroleiomyoma of 

 man. The author regarded the tumor as a fibrosarcoma. 



Thomas, 1927 b: In a codfish Gadus morhua a tumor 

 the size of an almond was present near the right ovary. 

 The cells are fusiform; confluent vascular spaces lined 

 by a rudimentary endothelium were abundant. The tu- 

 mor was likened by the author to the fibrosarcomas of 

 birds and mammals. 



Johnstone, 1927: Multiple small round cell sar- 

 comas were found in a turbot Rhombus maximus. Two 

 of the tumors were the size of a hen's egg and were 

 located on the pigmented side of the fish; nine addi- 

 tional nodules were found scattered throughout the 

 muscubture. None of the tumors were encapsulated; 

 the adjacent muscle was infiltrated. The cells were of 

 the small round cell type and appeared to be malignant. 

 The author believes that the numerous tumors were 

 multicentric in origin rather than metastatic. (Lympho- 

 sarcoma ?) 



DoMiNGtTiz, 1928: A 25 cm. goldfish Carassms aura- 

 (MS was observed to have had a nodule the size of a pea 



on its dorsal fin for 3 years. During the last year and 

 a hall the tumor had grown to a f i b ibVi of l.S cm. 

 Several days before death a few "teooDdiiy" nodulct 

 were observed oa the caudal fin. At antopsy, leveral 

 other tumors regarded as metastatic were founid in the 

 liver and elsewhere. The primary tumor was very vascu- 

 lar and soft. Histologically it consisted of eloogatcd 

 fusiform cells with krge oval nuclei. 



Takahasui, 1929: A tumor the siae of a fist tnae in 

 the trunk musculature of a dog sahnon Omeorkymkiu 

 heta. It was fluctuant, and was found to contain a 

 central area of liquefaction necrosis. Histologically the 

 tumor was composed of qundle cells that showed active 

 mitosis and infiltrated the surrounding musculature. 



Takahashi, 1929: On the left side of a dog safanoo 

 Oncorhynchus heta, 15 cm. anterior to the tail fin. was 

 a tumor 9x7 cm., lying athwart the lateral line. On 

 the opposite side wu a similar but smaller tumor. Both 

 were soft in consistency, showed Uquefaction ne cr osi s , 

 and infiltrated the surrounding muscle. The cells varied 

 in size and shape and were rich m cytoplasm. 



Takahashi, 1929: Scattered over the body surface 

 of a hump-back salmon Oncorhynchus gorhuscha were 

 9 tumor nodules ranging from OS to 3 cm. in diameter. 

 There was no sharp demarcation from the surrounding 

 tissue and on histologic grounds the author identified the 

 tumor, which was very celluUur and contained many 

 mitoses, as a round cell sarcoma. (Lymphosarcoma ?) 



Takahashi, 1929: In the middle of the trunk, above 

 the lateral line of a coalfish Theragra chalcogramma was 

 a tumor 4 x 3.5 cm. It was uniformly firm, and gray- 

 white. Microscopically the parenchyma consisted of 

 spindle cells, many of which were in mitosis. The sur 

 rounding tissue was infiltrated by the timior. 



Takahashi, 1929: An oval, subcutaneous tumor 

 larger than a hen's egg was found in the occipital regiao 

 of a coalfish Theragra chalcogramma. Except at its bate, 

 the tumor was well demarcated from the surrounding 

 tissue; mitotic figures were unccnnmon. The tumor wu 

 identified by the author as a spindle cell sarcoma. 



Takahashi, 1929: Eight tumors of varying rinet 

 were present in the subcutaneous tissue of a Japtneae 

 baas Lateolabrax japomcus. The author identified the 

 lesions as spindle cell sarcomas that were infiltrating 

 the surrounding tissue. 



Takahashi, 1929: In the pharynx of a Japanese 

 bass LaUolabrax japomcus was a tumor, 7.5 z 3 cm 

 Two similar lesions were present in the subcutansoos 

 tissue of the right side. HistologicaDy the parenchyma 

 consisted of spindle cells with few mitotic figures. 



Takahashi, 1929: On the dorsum of the neck region 

 of a kisugo Sittago j a^ oniM was a hemispherical, soft 

 elevation that measured 2.2 x 1.3 cm. and was gny- 

 white on section. It had infiltrated the adjacent tiisaes 

 and was identified by the author u a spindle cdl sar- 



Takahashi, 1929: A irascniar, gnjr. nktnrtad l»- 

 mor the size of a walnut wns prsssnl to tha trank onit- 

 culature of a gurnard UpU o phi ^ atafa. The tumor 

 celb were large and round with rather small nucld. The 



