194 EXPERIMENT STATION. [Jan. 



chemical methods. The two samples of urine also submitted for lead 

 and arsenic tests have been analyzed. Both of these samples showed a 

 reaction for lead and arsenic, but not to the extent that I had antici- 

 pated; only small quantities of either of these poisons were found 

 present. I did not attempt a quantitative determination in either case, 

 but should judge that the sample from the red cow (No. 3) showed the 

 larger amounts of both arsenic and lead. 



^&^ 



The fact that a young calf, to which large quantities of the 

 milk of cow No. 4 were fed, showed no symptoms of illness, is 

 further evidence that arsenic and lead were not present in the 

 milk. 



Brief Summary of Symptoms. 



Chronic Poisoning. — Loss of appetite, refusal of water, 

 purgation, with feces liquid and nearly black in color, contain- 

 ing an abundance of mucus and blood, the latter either disinte- 

 grated or in clots, suppression of urine, progressive paraplegia, 

 emaciation, with hair harsh and rough. There appears to be 

 but little disturbance of the temperature functions, the maxi- 

 mum reading obtained being only 103.2° E. The pulse becomes 

 somewhat accelerated and of a thready character, but is not 

 sufficiently altered to constitute an important symptom. There 

 is dullness of the eye and general indications of depression 

 when the symptoms enumerated above are most in evidence, but 

 with the elimination of the poison from the system there is a 

 gradual return of the normal body functions, as indicated by a 

 cessation of purgation and a return of the appetite. 



Acute Poisoning. — Attack sudden, characterized by shiver- 

 ing, refusal of food and water, back arched, skin dry and harsh, 

 hair erect, abdominal pain, slight elevation of temperature, 

 pulse thready and increased to 55 or 60 beats per minute, respi- 

 rations accelerated and difficult. Following these symptoms in 

 quick succession is purgation, with feces abundant, watery, dark 

 in color and bloody. The urine is scanty and passed only at 

 long intervals. Paresis develops early, with the other symp- 

 toms, and is progressive, affecting the posterior portions of the 

 body most. At this stage of development of the symptoms the 

 head is moved about nervously, the eyeballs are retracted and 

 glassy, there is more or less champing of the jaws, and at irregu- 

 lar intervals the animal suffers from convulsions, from which it 



