— 56 - 



applied, as an auxiliary in clinical dia- 

 gnosis. 



The proof by Tuberculine, limiting 

 the remarks to what has been done in 

 the Argentine, authorizes the following 

 conclusions: 



1°'. The simple dose, the same as the 

 double dose of Tuberculine, pro- 

 duces in many cases diagnostic 

 reaction, in the tuberculous sub- 

 ject, before 12 hours have elap- 

 sed (1). 

 2°. Reaction under the same doses 

 may disappear before the expira- 

 tion of the 12 hours referred to, 

 in the classical instructions gene- 

 rally folloved 

 3°. Repeated injections of tuberculi- 

 ne. in simple or double doses, 

 produce "accoutumance" in the tu- 

 berculous animals. 



I) Experiments on "accoutumance" by the Chiei 

 of the Quarantine Lazaretto, employing doses up to 

 r>u c.c. "I Tuberculine. 



