30 ACETANILID, ANTIPYRIN, AND PHENACETIN. 



WEINSTEIN, N. Ueber Calomel-Antifebrin-Kawa. Wien. ined. Bl., 1887, 10 : 305, 

 340. 



(1) Seven and one-half grains of acetanilid produced cyanosis of the 

 face in a woman 22 years of age, with puerperal fever. (2) The same 

 dose caused marked cyanosis in a woman 43 years old, with erysipelas. 



WIUOWITZ, J. Antifebrin bei fieberhaften Erkraukungen der Kinder. Wieu. 

 med. Wochenschr., 1887, 37: 572. 



Boy, 12, pneumonia : Intense cyanosis of the face and finger tips fol- 

 lowed the ingestion of each dose of 3 grains of acetanilid. 



WINNETT, H. J. Was it antifebrin? Therap. Gaz., Detroit, 1887 (3), 3: 646. 



Five grains of acetanilid every four hours were ordered for tonsilitis. 

 After 3 doses had been taken there appeared marked cyanosis with rapid 

 and feeble pulse. 



ISttS. 



APOTHEKER ZTG., 1888. Poisoning by antifebriue. Abs. in Med. News, Phila- 

 delphia, 1889, 54: 45. 



Ingestion of 0.5 drachm of acetanilid twice in twenty-four hours was 

 followed by cyanosis, anxiety, cold perspiration, and great depression. 



BBINGIEB, J. T. Antifebriue. Med. World, Philadelphia, 1888, 6: 377. 



In typhoid acetanilid in 4-grain doses caused copious sweating, depression 

 of the heart, thoracic oppression. The rise in temperature was in every 

 case accompanied by coldness of the extremities. 



DEMME, R. Ueber die Anwendung uud Wirkung des Salols, Antifebrius, und 

 Urethans ini Kiudesalter. Abs. in Internat. kliu. Kimdschau. Wien, 1888, 

 i: 118. 



Boy, 11, phthisis: One and one-half grains of acetanilid five times a day 

 causes cyanosis. Acetanilid produced profuse diarrhea and nausea in a 

 girl and a boy suffering from erysipelas. 



FBEUND, C. S. Ein Tall von Antifebriuvergiftung. Deutsche med. Wochenschr., 

 Leipzig, 1888, 14: 834. 



Man, 29: Took 45 grains of acetanilid at 11 a. m. and again at 2 p. m. 

 By 5.30 p. m. he was deeply cyanotic and his pulse hud increased hi 

 rapidity to 152. Cyanosis lasted about four days. 



HARDY. Brit. Med. J., London, 1888, 1: 661. 



Report of a case in which sudden death followed the eighth administra- 

 tion of a 15-graiu dose of acetauilid. 



KLIPPEL, C. Antifebrin Its value as a therapeutic agent. Kansas City Med. 

 Rec., 1888, 5: 441. 



(1) Woman, age 21, acute metritis: Three 4-grain doses of acetanilid at 

 intervals of three hours caused cyanosis and dyspnea; 3-graiu doses subse- 

 quently gave similar symptoms. (2) In two other cases the symptoms were 

 like those mentioned above, but not so marked. 



KRONECKER. Einige Beobachtungen liber die Xeben-Wirkuugen des Antifebrins. 

 Therap. Monatsh., Berliu, 1888, 2: 426. 



Youth, 18, typhoid : Profuse perspiration and collapse, passing into coma, 

 followed the administration of 3 grains of acetauilid. 



