LITERATURE ON ACETANILID POISONING. 35 



IK. I. N. Case of antifebrin habit. New Orleans, Med. and Surg J 

 1889-90 (n. s.), 17 (2): 896. 



rase is n -ported to illustrate the insidious onset of the acetanilid 

 habit and its pernicious effect on the blood. Man, with necrosis" of the 

 tibia, took aeetanilid in large doses for pain. He became addicted to its 

 use, and is said to have taken as much as a teaspoonful at a time. The 

 evil effect on the blood was shown by the excessive pallor of the skin. 



TAYIOI:. w. II. I teport of toxic effect of acetanilid. Cincinnati Lancet-Clinic 

 1890 (n. s.), 24: 683. 



(1) Woman. l';. advan.-ed in pregnancy, urine contained albumin: At 

 5 p. ni. and 7 p. in. she took 5-grain doses of acetanilid. At 10 p. m. her 

 physician found her givatly prostrated with deep cyanosis, pinched features, 

 subnormal temperature, cool moist skin, and headache. Her temperature 

 remained subnormal for ten days. ILM Woman, 19, six months pregnant: 

 Wan given in -rains of aeetanilid for fever. Her temperature fell rapidly 

 to '.if, . polK ran up t<> ll'n. .-uid skin became moist and cool. There was 

 slight cyanosis and some prostration. 



TMOM\>. w. II. Aeetanilid. i:.-prt of a fatal case. Indiana Med. J., Indian- 

 a|H,lis, 1890, 9: 8T. 



i 1 Anihor .-\presses tin- opinion that ."> grains of acetanilid caused the 

 death of ,i \\oman sntTerini: from neuralgia of the head and stomach. May 

 1. ai I p. m.. the patient's temperature was 104 and her pulse 120, full and 

 sin.ni:. She ATM md given .". grains of acetanilid. Her tempera- 



ture fell rapidly, ar.-ompanied by symptoms of collapse, and she died nine 

 hours after takinu' tin- AtMi V reeord of autopsy. (2) Ingestion of 10 

 -rains of acetanilid was followed by symptoms of collapse. 



YIIKIMII .1. Ilin 1 'all \ on . \ntifebrinvergiftung. St. Petersb. med. Wochenschr., 

 189n V r . 7: 1M 



Wi-inan i""k two ti-aspiNinfuls of acetanilid on an empty stomach. She 

 \omit.-d afier ilriiiking milk and then a solution of alum, but cyanosis 

 appeared, and she went into a state of collapse which lasted three hours. 



\\OIM. .1 Kin Kail von Antlfebrinvergiftung. Deutsche Med.-Ztg., Berlin, 

 1890, 11: 535. 



Woman, 40: Took 7.5 drachms of acetanilid with suicidal intent. This 

 was followed by collapse and coma, and in addition hematuria. 



1801. 



I'.KO.NNKK. H. Case of pus in the pericardium treated by incision and drainage. 

 Brit. .Med. .J.. London. 1891, 1:350. 



(Jirl. 11 : A single dose of 7.5 grains^ of acetanilid caused a rapid fall in 

 temperature and symptoms of collapse. 



.1 It. riinieal observations of acetanilide. Med. Surg. Reporter, Phila- 

 delphia. is'M. <;:>: 72ft 



Girl. U : A 4-grain dose of acetanilid caused cyanosis and collapse. 



IMNX,,\N. T. M. Subnormal temperature from antifebrin. Memphis Med. 

 Month.. iyl. 11 : 123. 



Man. 40: The ingestion of 14 grains of acetanilid in 2 doses caused 

 cyanosis and subnormal temperature. 



