36 ACETANILID, ANTIPYRIN, AND PHENACETIN. 



EASLEY, E. P. Fatal case of acetanilide poisoning. (Letter to editor.) Amer. 

 Pract. and News, Louisville, 1891, 12 : 178. 



Woman, 22, took by mistake 24 grains of 1 antikamnia, supposed to repre- 

 sent 18 grains of acetanilid. In a few minutes she was wildly delirious. 

 She then became unconscious. Death occurred about ten hours after 

 ingestion of the drug. There was deep cyanosis of the entire body. 

 Autopsy failed to show any lesion as a cause for death. 



HABE, H. A. Fever: Its pathology and treatment by antipyretics. Phila- 

 delphia and London, 1891, p. 89. 



A dose of 5 grains of acetanilid caused collapse in a case of typhoid 

 fever. 



HAWKINS-AMBLEB, G. A. Antifebrin in typhoid fever. Brit. Med. J., London, 

 1891, 1: 172. 



(1) Woman, 49, typhoid: Four grains of acetanilid caused collapse. 

 (2) Woman, 35, typhoid: A dose of 4 grains of acetanilid caused marked 

 prostration. 



HORTON. F. Prolonged subnormal temperature following the administration of 

 antifebrin. Med. News, Philadelphia, 1891, 59: 712. 



A typhoid fever patient was given 4 grains of acetanilid and three- 

 fourths of a grain of camphor at 10 a. m., and the same dose at 3 p. m. 

 At 6 p. m. the temperature, which had been 104, was 97. It ran between 

 this and 94.6 for forty-eight hours, when it rose rapidly to 104. 



SPENCEB. Poisoning by antifebrin. Canad. Pract., Toronto, 1891, 16: 163. 



Child, 5, whooping cough: Ingestion of a drachm of acetanilid taken by 

 mistake caused deep cyanosis and slowed respiration. 



1893. 



GRIEB. W. F. The toxic effects of antifebrin complicated with alcoholism. 

 Med. Rec., New York, 1892, 42: 511. 



Woman, 45: Ingestion of 40 grains of acetanilid within eleven hours 

 caused marked cyanosis, increasing rapidity of the pulse, swelling of the 

 tongue, and great restlessness. 



J. W. C. Case of acetanilide poisoning. Med. Rev., St. Louis, 1892, 25 : 412. 



Woman, 36, influenza : Took about 40 grains of acetanilid in divided doses 

 within four hours. There followed cyanosis of the face and lips, semi- 

 consciousness, delirium, and symptoms of collapse. 



KBONFELD, A. Ueber Antifebrinvecgiftung. Wien. med. Wochenschr., 1892, 

 42: 1457. 



Man, 24: Took 3 drachms of acetanilid with suicidal intent. Within 

 thirty minutes this was followed by dizziness, nausea, pain in the region of 

 the stomach, unconsciousness, and slight cyanosis. 



WABFVINGE, F. W. Redogorelse for de forgiftningsfall som forekommit & 

 Sabbatsbergs sjukhus under aren 1879-91. Antifebrin. Hygiea Stock- 

 holm, 1892, 54 (1) : 238. 



Reports two cases of poisoning by acetanilid. Both patients recovered. 



