LITERATURE ON ACETANILID POISONING. 37 



18Q3. 



Iti ii. <;. \ Mer Faile von Antifebrinvergiftung. Memorabilien, Heilbronn, 1893, 

 88 (N. F. 13) : 535., 



(1) Man, past 70: Ingestion of a heaping teaspoonful of acetanilid was 

 followed by cyanosis and symptoms of depression. (2 and 3) Each patient 

 tiM.U ono-half teaspoonful of acetanilid. One complained of dizziness, weak- 

 ness, shortness of breath, and cyanosis of the finger nails, and the other 

 slept for two hours. (4) Woman, 75: Ingestion of an ounce of acetanilid 

 in rive .lays, in teaspoouful doses, was followed by weakness, drowsiness, 

 and dyspnea. 



KOKAWA, I'. Antifel.rin jutokusei Shiken (antifebrin poisoning). Tokujima 

 U-akkwai Xashi.. iv.:i. No. KJ, p. s. 



!>A\ \ r.-port ,,f ilin-e oases of addiction to the coal-tar derivatives. 



Arner. Med.-Surg. Bui., 18JM, 7: 1490. 



(1) Man. ;:,; riironi. bronchitis and cardiac palpitation for two years. 

 Pulse KM i Mini weak. iMNtuiiiiig irregular upon exertion. Anorexia, consti- 

 pation. .-. \aryintf in degree at different times. Had been addicted 



to the use nf a.-etanilid for a year. taking in to 60 grains daily. Last two 

 months h. had hern runnini: down until he was confined to bed. Dose of 

 acetanilid was n-dn.-ed to lu grains daily. He gradually improved and at 

 end of a year was in fairly good health. (2) Man, 32: Suffered from 

 cyanosis. coldness of extremities, insomnia, anorexia, constipation, nervous- 

 ness, ami am-mia. Trim-: Sievitir gravity 1.012, albuminous. Heart, rapid 

 and tWI.le. Had hern taking acetanilid for eight months, 12 to 40 grains 

 daily, and hlH health had failed rapidly. The drug was entirely withdrawn 

 and afier a month he was In fairly good condition. After abstaining for 

 ,1 months h- attain .-ontra. -trd the habit and his health again became 

 impaired. 



Hiir.iui. l: IIochgrailiv:<' Aml>lvopie nach Gebrauch von Acetanilid. Memora- 

 bilien, Ileilbmnn. \^( i N. F. i. 14: 65. 



Ingestion of three 15-graln doses of acetanilid at short intervals caused 

 vertiu'o and dimness of vision. After twenty-four hours the sight was 

 again normal. 



I.YNBOMNDROFF, P. F. Sluohal otravleniya antifebrinom (Antifebrin poisoning). 

 Voyenno-Med. J., St. Petersburg, 1894, 181 (unofficial pt, sec. 2) : 29. 



MORTON, T. S. K. Acetanilid as an antiseptic. Proc. of the Phila. Co. Med. 

 Soc., 1S1M. l."i: 4t59. 



(1) Infant, 14 months: Large wound in hip, packed with 10 per cent 

 acetanilid jrauze. In four hours the temperature dropped 5, with symp- 

 toms of marked depression. (2) Man, 57: Extensive superficial scald. 

 Two drachms of acetanilid dusted over the surface caused cyanosis, ex- 

 cessive yawning, delirium, and symptoms of depression. 



, Q. W. The use of a.-etanilid in medicine and surgery. J. Amer. Med. 

 Assoc., Chicago, 1894, 28: 100. 



Tlie application of acetanilid powder to an ulcerated surface was followed 

 by deep .van. .sis of the nose, lips, and tips of the fingers and toes. 



