LITERATURE ON ACETANILID POISONING. 41 



SIMMKRS, O. R. Acetanilid idiosyncrasy. Indiana Med. J., Indianapolis, 1899- 

 10OO, IS; *>SL. 



Woman, 26 : Ingestion of 8 grains of acetanilid in 2 doses with an interval 

 of one-half hour caused nausea, vertigo, dyspnea, deep cyanosis of lips and 

 linger tips, aud all the symptoms of collapse. There were also periods of 

 convulsive movements with partial loss of consciousness. 



ieoi. 



EARI>. s i: A case resembling morbus cseruleus probably due to a dusting 

 powder containing acetanilid. Pediatrics, New York, 1901, 12; 93. 



< 'hild. one month old : Thought at first to have morbus caeruleus. Cyano- 

 sis of skin and mucous membranes. Lips and tongue almost black. Cold, 

 clammy skin, mental dullness, slowed respiration. Later it was ascertained 

 that a raw an -a of skin had been dusted for several days with a powder 

 ci insisting of equal parts of acetanilid and boric acid. 



MANASSKS. J. I.. Two cases of acetanilid poisoning in children from absorption 

 from external wounds. Internal. Med. Mag., New York, 1901, 10: 278. 



i 1 child. '. weeks old: Frequent application of a powder consisting of 

 equal parts of ao-ianilid and subg.-illate of bismuth to an inflamed area on 

 the buttocks was followed ly deep cyanosis of the entire skin. (2) Boy, 2$ 

 ^ milar |x>wder dusted on a scalded surface caused cyanosis of 

 lips, ears, and finger tips, extending to the entire skin, and symptoms of 

 depression. 



STEWART, 1 . T Toxic effects of acetanilid. Philadelphia Med. J., 1901, 8: 379. 



i 1 ) A denuded surface, made by taking skin grafts, was copiously dusted 

 with acetanilid. Next morning the patient was cyauotic, collapsed, and 

 unconscious, ii'i OiiM. I months: Application of a powder consisting of 

 one halt" drachm of calomel and two drachms each of bismuth subgallate 

 and acetanilid to the skin was followed by intense cyanosis. 



TRACT, E. A. Acetauilid poisoning. Pediatrics, New York, 1901, 12: 385. 



I :a by. few lays old : Application of a powder consisting of equal parts of 

 acetanilid and stearate ,,f x.inc to a raw area on the buttocks several times 

 in twenty-four hours was followed by intense cyanosis. 



1903. 



CABOT. R. <'. Methemoglobinemia due to acetanilid but without any marked 

 constitutional symptoms. Philadelphia Med. J., 1902, 10: 848. 



Man, 35. entered hospital in July in a condition of intense cyanosis. 

 Six months l*?fore he had begun to take acetanilid for pain, and had con- 

 tinued to take about six 5-grain powders daily. Blood drop, chocolate 

 colored; urine brownish-red and gave spectrum of methemoglobin. 



KIKINPETER, E. A. Acetanilid cyanosis. New Orleans Med. and Surg. J., 

 1902-3, 55: 166. 



Adult, male: Five grains of acetanilid administered every four hours 

 for three days caused marked cyanosis of lips, gums, and mouth, and 

 marked prostration. 



