LITER ATUBE ON ACETANILID POISONING. 43 



. D. D. Chronic poisoning by acetanilid. J. Amer. Med Assoc Chi- 

 Ca*0, I 1 -*":.. 44: 



(1) Man, 4(> : Habitual use of acetanilid for two years caused gradual 

 loss of health, cyanosis, general debility with loss of cardiac tone, and 

 deterioration in tlu> quality of the blood. (2) Man, 50: Habitual use of 

 acetanilid for two years caused progressive loss of flesh and strength, 

 tin- wri^ht fallim: from 14O to IK',, frequent vomiting, cyanosis, deteriora- 

 tion in the quality of the blood, mental dullness, and general debility 

 amounting to invalidism. 



1906. 



AUSTIN, A. F... ami I. \KK\r.i i . II. ( '. Acetanilid poisoning from the use of pro- 

 prietary headache powders. J. Amer. Med. Assoc., Chicago, 1906, 46: 1680. 



Woman. :; : Habitual use of nervease powders (about 5 grains of acet- 

 anilid each i. often i to lo daily, caused intense cyanosis and deterioration 

 in the quality of the blood. (2) Woman: Habitual use of 6 nervease 

 powders daily caused nausea, general debility, cyanosis, and deterioration 

 in the quality of the blood. 



BEBGMAV \ ll* -marks on acetanilid. ('Unique, Chicago, 1906, 27 : 271. 



(1) Administration of two 5-grain doses of acetanilid with an interval of 

 one hour to a baby '_' weeks old was followed by coma, cyanosis, and col- 

 j i T\\o hundred grains of acetanilid taken within twenty-four 

 honr> .-an "i-d c\aiio>is. profound coma, and death. 



I'.i \. KIM K\. \ i: A- ,-tanilid poisoning from bromo-seltzer. J. Amer. Ivied. 

 ABBOT., rincauo, IM8, <;: i7rr. 



Man. _"_': Habitual use of broino-selt/er over a period of six months 

 caused nu-ntal dullness and depression, general weakness and indisposition 

 i.. exertion, and e\anosi>. The expression was vacant, the breath fetid, 

 pulse rapid on exertion. 



CABKAIIY. D. A.-ei.-uiiiid poisoning' by headache tablets. J. Amer. Med. Assoc., 

 Uiieairo. 1906 17 : "I'-'- 



Woman. 45: Accustomed to taking "Steam's Headache Cure." One 

 \\afer an h..ur f..r ihree hours caused cyanosis and symptoms of collapse. 



i-. ii. \| \ C*M "f a.etanilid poisonini; from absorption. J. Amer. Med. 



hicau-o. I-.MM;. 47: :::,!. 



Woman, 37: (1) For eleven months she had dressed an ulcer of the leg 



with acetanilid. and during this time she had run down in health and lost 



7> |H,unds. Sum-red from cyanosis, abdominal pain, general nervousness, 



dyspnea, naus.-a and occasional vomiting, headache, and dizziness. Urine 



dark, amber tint. IJIood examination showed anemia. (2) Habitual 



Of an amount of bromo-selt/er, equivalent to about 50 grains of acet- 



nnilid daily. 



Hi MI N\\ \Y. II. P.. Death from bromo-seltzer: case of acetanilid poisoning. J. 

 Amer. Med. As^.,-.. Cbica-o, 1906, 47: 2158. 



Woman. :;i : I Miring the last month she had suffered from headaches for 

 which she took bromo-selt/er. On October 12 she took an unknown quan- 

 tity. Vomited before arrival of physician. Examination showed a poorly 

 nourished woman, breathing regularly and deeply. Eyes closed, body re- 

 laxed. lips and lingers blue. Pulse 80, soft and regular. Area of heart 

 dullness slightly increased, right ventrical dilated. Pupils dilated. She 

 sank suddenly and died at 7.45. Verdict of coroner's jury: "Death from 

 acetanilid potoooillg from taking bromo-seltzer." Autopsy showed soften- 

 Ot the kidney from parenchyrnatous inflammation. This condition had 

 iris en no symptoms during life. 



