8 



ACETANILID, ANTTPYRIN, AND PHENACETIN. 



the brain as contradistinguished from the idea of a food for the whole body, 

 thon it is and I so chanjo you in this first prayer misleading, and therefore 

 a violation of the law. 



The information submitted in the following pages with regard to 

 the number of instances quoted in the literature of the subject in 

 which poisoning, death, or habitaal use has been known to result 

 from the administration of acetanilid, antipyrin, and acetphenetidin 

 is summarized in section A of the table following. 



The information as tabulated in section B was furnished by 400 

 physicians, in reply to letters of inquiry issued by the Department. 

 Nine hundred and twenty-five of these letters were sent out, and 400 

 replies were received. Granting that the 525 physicians who did not 

 reply had no cases to report, the question may profitably be asked, if 

 925 physicians have observed 814 cases of poisoning by these drugs, 

 28 deaths which were attributed to their use, and 136 instances of 

 habitual use, how many such cases have in all probability been ob- 

 served by the 125,000 physicians scattered throughout the United 

 States? The first summary, C, includes both the number of cases 

 recorded in medical literature and those reported by physicians. 



Cases in which deleterious or fatal effects have been produced by acetanilid, antipyrin, and 



acetphenetidin. 



A. CASES RECORDED IN MEDICAL LITERATURE, 1884-1907. 



B. DATA REPORTED BY PHYSICIANS. 



C. TOTAL OF COLLATED CASES (A AND B). 



