LITERATURE ON ANTIPYRIN POISONING. 67 



Alarming prostration followed the administration of 5 grains .of anti- 

 pyrin to a very fat woman with weak heart walls. 



lees. 



188S - Rev * mM> de la Suisse rom - 



Author cites a case in which a dose of 7.5 grains of antipyrin was fol- 

 lowed by swelling of the eyelids, an itching eruption, nausea, vertigo, pre- 

 cordial pain, and loss of consciousness. 



D'EsPiNK, cit.-d l.y Cordet in discussion of paper on " Des accidents produits par 

 I'antipyrine." Uev. gen. cliu. therap., Paris, 1888, 2: 709. 



Author states that he had seen collapse m children with pneumonia 

 follow the Ingest ion i if even small doses of antipyrin. 



DBAHCHK. Ueber die Nebenwirkungen des Antipyrins. Wien. klin. Wochen- 

 -.. L886, 1 : -",71. 



Typhoid : An enema containing 0.5 drachm of antipyrin was followed by 

 a eopi..us hi'iinrrli:iL'ie exanthem and collapse, which ended fatally. 



IlAKFTKK. K. COT.-Bl f. schwei/. AeN/e. P.asel, 1 SS.S. IS: 74.,. 



Man. ;:;. puriiiiKiuia : 1'atal eol lapse occurred one hour after the inges- 

 of 15 grains of aniipyrin. 



M"i i M 1:1 . II . :i. . I l.\ iv-er in "Les traitements de typhoidiques." Bui. med., 

 1'aris. [888, '-': Ml 



(1) Typhoid patient. .VJ years of age, after taking antipyrin for fifteen 

 I, died ..f . a, h.'.-ti.- pnrpun-a and debility induced by the drug. (2) In- 

 geation of antipyrin by a typhoid-fever patient 26 years old caused uremic 

 nviilsiniis. \vhi.-h e:nltil fatally. 



LOOL, .1. .M. lirfahrniigen Uber Antipyrin. Wien. med. Presse, 1888, 29: 121. 

 Child, 0. typhoid : Ingestlon of four doses of antipyrin, 3.25 grains each, 

 was followed l>y eyaimsis and symptoms of collapse. 



Mi i i IK. II. Irl., r toxischr Nelieiiwirkungen des Antipyrin. Cor.-Bl. f. 

 Schw.'i/. Aerxte. Itasel. 1S88, 18: 681. 



Cirl. H>. acute articular rheumatism: Each dose of 11 grains of anti- 

 pyrin was followed by nausea, dizziness, itching, and a tendency to col- 

 lapse. 



PATMK DbKaMtoa of paper by R. H. Lewis. North Carolina Med. J., Wil- 

 mington. L888, '2\ : m\ 



In-.'estion of s grains of antipyrin was followed by collapse. 



RAPI.N. K. Accidents dus a 1'autipyriue. Rev. med. de la Suisse rom., Geneve, 

 1888, 8: 687. 



Woman, 28, sciatica : The ingestion of 1-grain doses of antipyrin for six 

 days was followed by cyanosis, symptoms of collapse, and the appearance 

 of an itching eruption. 



Des accidents causes par 1'antipyrine. Rev. gen. clin. therap, 

 I 'ads, 1888, 2: 515. 



The ingestion of 7.5 grains of antipyrin was followed by itching of the 

 fa. ... swelling of the eyelids, and symptoms of collapse. 



