68 ACETANILID, ANTIPYRIN, AND PHENACETIN. 



SYKES. Discussion of paper by R. H. Lewis. North Carolina Med. J., Wil- 

 mington, 18SS. 21: 297. 



(1) Two doses of 10 grains each of antipyrin caused collapse and death 

 in a girl of 10. (2) Typhoid: Ten grains of antipyrin caused coma and 



collapse. 



1889. 



CROMBIE. A. The comparative value of antipyrin, antifebrin, and phenacetin as 

 antipyretics. Practitioner, London, 1889, 43: 270. 



A case in which collapse followed the ingestion of antipyrin. 



v. KOGERER. Antipyrinbehandlung des hektischen Fiebers. Wien. klin. 

 Wochenschr., 1889, 2: 778; 802. 



Out of 100 cases of phthisis in which antipyrin was given, erythema was 

 noted in 2 instances and collapse in 1. The administration of antipyriu to 

 the same patient on two occasions was followed by collapse. 



PURDON, C. S. Intolerance of antipyrin. Brit. Med. J., London, 1889, 1 : 1345. 

 Man, 50, sciatica : A 5-grain dose of antipyrin was followed by severe 

 nervous symptoms, cyanosis, and collapse. 



YViNt.RAVE. T. Ill effects of antipyriu. Lancet, London, 1889, 2: 313. 



Woman, 21 : A dose of 10 grains of antipyrin was followed by dyspnea, 

 loss of power on the left side, the appearance of an eruption, and symptoms 



of collapse. 



189O. 



SCHWABE. Fall von aknter Antipyrinvergiftung. Deutsche Med.-Ztg., Berlin, 

 1890, 11: 501. 



Woman, 22. neuralgia : A dose of 15 grains of antipyrin was followed 

 by dyspnea, complete blindness lasting thirty minutes, and symptoms of 

 collapse. 



SPITZER. F. Selbstmordversuch mit Antipyrin. Centrbl. ges. Therap., Wien, 

 1890, 8: 134. 



The ingestion of 2 drachms of antipyrin within an hour was followed by 

 swelling of the face and eyelids and symptoms of collapse. 



1891. 



W ATKINS. It. L. A case of antipvrine poisoning. New York Med. J., 1891, 51: 

 314. 



Woman, 30: A dose of about 20 grains of antipyriu was followed by 

 symptoms of cyanosis, collapse, and an eruption of white blotches. Tlie 

 after effects lasted two months, during which time she suffered from weak- 

 ness, palpitation of the heart, and an occasional reappearance of the 



eruption. 



1893. 



GUTTMANN, P. Ueber einen Fall von Antipyrin-Vergiftung. Therap. Monatsh., 

 Berlin, 1892, 6: 560. 



The ingestion of 2.5 drachms of antipyrin, in 15 doses, twice daily, was 

 followed by transient blindness, the appearance of an eruption, and symp- 

 toms of collapse. 



1893. 



KRYSINSKI. St. Przypadek otrucia antypiryna. Gaz. lek., Warszawa. 1S93 

 (2 s.), 13: 1031. (Abs. Sajous, 1S95/5: A-33.) 



Girl. 20: Ingestion of 81 grains of antipyrin was followed by symptoms 

 of collapse. 



