72 ACETANILID, ANTIPYRIN, AND PHENACETIN. 



1894. 



LEPINE, R. Stir les accidents produits par 1'antipyrine. Semaine med., Paris, 

 1894, 14:121. 



Woman, 53 : On three occasions a 5-grain dose of antipyrin was followed 

 by enormous swelling of the lips and tongue, coma, involuntary evacuations 

 of bladder and bowels, and marked prostration. 



BUTTON, A. Toxic symptoms induced by antipyrin and chlorate of potash. 

 Australas. Med. Gaz., Sydney, 1894, 13: 43. 



Young woman, headache: A dose of 5 grains of antipyrin was followed 

 by the appearance of a bright red rash and symptoms of marked depression. 



1896. 



SCHEEL. Ein Fall von Antipyrinvergiftung. Cor.-Bl. allg. Mecklenb. Aerzte, 

 Rostock (1896), 1893-97, Nos. 151-187, p. 389. 



Woman, 50, headache: Ingestion of 8 grains of migrainine was followed 

 by swelling of the tongue, upper lip, pain in the eyes and lachrymation, 

 a scarlatiniform eruption, and marked prostration. 



1897. 



DUCHENNE. Intolerance excessive pour 1'antipyrine. Med. mod., Paris, 1897, 

 8:167. 



The ingestion of 12 grains of migrainine was followed by marked pros- 

 tration and the appearance of an erythematous rash with the subsequent 

 development of blisters. 



WALLACE, F. G. Poisoning by antipvrin ; recovery. Lancet, London, 1897, 1 : 

 409. 



Woman, convalescent from typhoid : Administration of 10 grains of anti- 

 pyrin in aromatic spirits of ammonia and water was followed by temporary 

 blindness, a bright red eruption, dyspnea, and great depression. 



WEBSTER, E. Antipyrin poisoning. Brit. Med. J., London, 1897, 1: 458. 



Ingestion of 5 grains of antipyrin in a sedative mixture was followed 

 by great swelling of the face, dyspnea, cyanosis, an eruption, and marked 

 prostration. 



19O3. 



SEILER, D. Ein Fall von Antipyrin-Intoxikation. Cor. Bl. f. schweiz. Aerzte, 

 Basel, 1902, 32: 470. 



Woman. 26, acute rheumatism : After having taken about 3 drachms of 

 antipyrin in divided doses there appeared edema of the face and a scarla- 

 tiniform eruption with marked depression. 



1904. 



LANDRIEUX ET ROUSSEAU. Intoxication par 1'antipyrine. Bui. med., Paris, 1904, 

 18: 357. 



The ingestion of 0.5 drahm of antipyrin was followed by very intense 

 dyspnea, swelling and redness of the face, coryza, and prostration. 



190-7. 



AZEMA. Sur un cas d'intoxication par 1'antipyrine. Toulouse med., 1907 (2. s.), 

 9: 111. 



Woman, 42 : Six doses of antipyrin of 7.5 grains each within three hours 

 were followed by vertigo, persistent vomiting, unconsciousness, and marked 

 prostration. 



