LITKKATriJK >N AXTIPYRIN POISONING. 77 



1-- (T. 



UK Tt i.i.io. P. I/Miitipirina iu-1 renmatismo articolare aento. Progress ined 

 Napoli. IXXT. 1: '.nil. 



The iiiL'estion nf antipyrin by a patient suffering from articular rheuma- 

 tism \v.-is followed l.y a transient albumiiiuria. 



1888. 



Ron. IN. L. observation d'a.-ridents fehriles produits par 1'antipyrine Bui 

 mem. S4K-. med. prat.. Paris. Isss. p. 478. 



i of 7 .r, gralni of aniipyrin hourly for four hours was followed 

 ly a severe rhill. delirium. vomiting. and suppression of the urine. 



18! 1 . 

 , II. .M. V.ies on a <-:ise of poisoning by antipyrine. New York Med. J., 



M.in. ."..",. ln-:ni.i IM- : Soon aft-r th> in.^estion of GO grains of antipyrin 

 within thirty hours tin- nrin.- L.-rain.' dark nlive-green in color. It con- 

 taiiMNl a small quantity of albumin and a few casts. Secretion scanty. 

 Symptoms disapiMsmil in tin- ronrse of two or three days. No evidence 

 of pn-\i<>nx renal disease. 



Tov I. AllMiiiiinuria caused by antipyrine. Virginia Med. Month., 



lli.-hmoml. iv.i :_'. |H : 105. 



Man. liM-omotot aia\ia Took for pain each night about 60 grains of 

 antipyrin. l-:iitriv<I I In- hospital with ihm:i of the legs and eyelids. The 

 urine was BO full of albumin that it soliditied on boiling. Albumin was 

 abundant in tin- morning and sranty in tlu evening. When the drug was 

 discontinued tin- albnminuria disappeared and the edema diminished. 



I- 1 . 



RAMOS, I . Albuminuria pr.Hln/.ida pop altas doses de antipyriua. Brazil-med., 



i:i.. d.- J isor. !: - 



SI-VNMI Ml -I l:in>'.-i-s ! 1'ant ip\ riiu- dans IVrvsipeh'. Semaine med., Paris, 



' 



Three east's in which the ini:i>stion >f antipyrin was followed by anuria, 

 with ureat r. M and mark-l depression. One case terminated in 



death. 



1898. 



am. Bui. soc. franr. dermat. syph.. Paris, 1898, 9: 193. 

 An intense -eneral unie.iria followed the ingestion of antipyrin, and an 

 antipyrin tampon inserted for epistaxis caused vesicatiou and symptoms of 

 nrethro-cystitis. 



>VM1MOMS OF CORYZA. 



1888. 



H. C, Miosynerasy to antipyrin. Brit. Med. J., London, 1888, 1: 695. 

 Woman, headache : < >n two occasions the ingestiou of antipyrin was fol- 

 lowed by symptoms of coryza and severe paroxysms of coughing. 



