GLANDERS, 361 



mercury, &c. ; hellebore, aconitum, digitalis, hyoscyamus, 

 cicuta, belladonna, &c. &c., but all without any specific or 

 curative effect.' The late Mr. Sewell appears to have been 

 more successful with the sulphate of copper {blue vitriol) ; 

 but as the benefits were generally confined to cases not 

 marked with much constitutional affection, so the value of 

 the remedy is necessarily much limited. To increase our 

 remedial means, Mr. Vines also has lately revived the sti- 

 mulating plan of treatment, and given it new publicity by 

 his reasoning and experiments. He observes, the remedies 

 which are to be employed in those cases that are likely to 

 run into, or have already become, what is usually termed 

 glanders or farcy, are those which possess stimulating and 

 tonic properties, separately or united. Of these a reference 

 to Mr. Vines' work will show that he places his principal 

 dependence on cantharides ; which have long been before 

 the public as a remedy for nasal gleets, but have never re- 

 ceived such ample elucidation as by this author. He gives 

 them every or each other day, in the form of a ball ; either 

 morning or evening (he, however, prefers the evening), 

 with ginger, gentian, and caraway seeds. He commences 

 with four or five grains of the cantharides, in fine powder, 

 according to size, age, condition, &c. ; and, if well borne, 

 the dose, after ten days or a fortnight, is increased to 

 eight grains, according to the circumstances alluded to. 

 When this larger dose has been in use some time he desists 

 altogether from the medicine for four or five days, and then 

 recommences, but with the smaller dose. 



Mr. Bracy Clarke's formula of administration of cantha- 

 rides, in conjunction with mineral tonics to be given daily, 

 is as follows : — 



Sulphate of zinc (jwhite Titriol) fifteen grains. 



Powdered cantharides seven grains. 



Powdered allspice fifteen grains. 



We cannot conclude without recommending the reader 

 to turn to the encouraging account of the effects of barytes 

 in glanders, administered by Mr. W. Percivall, which will 

 be found fully detailed in his most excellent work entitled 

 ' Hippo-pathology.' 



Glanders is communicable to the human subject. — Ample 

 experience will demonstrate the necessity there is that the 



