202 CLASSIFICATION OF THE MICRO-ORGANISMS. 



The individuals chiefly affected were those who had to 

 do with animals and animal tissues, such as tanners 

 butchers, &c. Cordua was able to cultivate cocci from 

 the affected portions of skin, and they formed in 24 86 

 hours on agar at 36 C. luxuriant chalk-white colonies, 

 with slightly facetted margins. Inoculations on animals 

 were without result, but here, also, he was successful in 

 setting up the affection on his own arm from a cultiva- 

 tion. Probably Kosenbach and Cordua have been dealing 

 with cultivations of the same organism which presented 

 different appearances only in consequence of differences 

 in the nutritive substrata. Further investigations must 

 be awaited. 



Imperfectly 

 known patho- 

 genic micro- 

 cocci. 



Micrococci have also been described as causal exciting 

 agents in numerous other diseases in man, but they have 

 been demonstrated either by microscopical investigation 

 alone, or the infective and cultivation experiments are 

 not free from objection, and therefore further con- 

 firmation appears to be necessary. To these belong * 



Variola. Cohn, Weigert, Koch, and others, found 

 micrococci in the pustules and in various internal organs 

 in persons who died of smallpox. Cultivations have not 

 yet been made. 



Vaccinia. In the lymph in the vesicles micrococci 

 have been frequently observed; cultivations of cocci 

 have also been repeatedly obtained from the lymph, but 

 all the micro-organisms as yet cultivated are evidently 

 only impurities for the most part of a saprophytic 

 character, as a vaccine pustule has never been produced 

 by inoculation of the cultivations. The recent cultiva- 

 tion experiments by Wolff do not seem to have given 

 a better result. 



Scarlatina, Measles. Micrococci found, but of no 

 importance (see Lit., p. 35). 



Diphtheria. In the former investigations by Klebs, 

 Oertel, and others, these authors evidently did not work 



As to the Micrococcus pneumonice see under " bacilli." 



