BACILLUS TUBERCULOSIS, 



263 



takes on the nuclear stain, and in which there are very 

 few or no tubercle bacilli; from the infectivity of the 



Fig 74. Miliary tuberculosis 

 of the lungs X 700. 



Fig. 



75. Tuberculosis of the 

 intestine X 700. 



cheesy centre the conclusion may, however, be drawn that 

 the bacilli have here passed into the spore stage, which 

 cannot be demonstrated by staining. 



As soon as giant cells appear in the tubercles, tubercle 

 bacilli are almost al- 

 ways found in them . / ^1 

 They often contain 

 only one bacillus, 



and then a peculiar 

 antagonism is fre- 

 quently evident 

 between the nuclei 

 of the giant cells 

 and the enclosed 

 bacillus. The latter 

 takes up a position 

 opposed to the 

 nuclei, and lies as 



<HK? | 

 III 



W. 



Fig. 76A. Giant cell from a case of miliary 

 tuberculosis X 700. 



far as possible in the part of the cell which is free from 

 nuclei (fig. 76fi). If the number of tubercle bacilli 

 which develop in the giant cells increases markedly, they 

 finally break through the wall of nuclei, and the giant 

 cell then apparently dies. 



