BACILLUS CAVICIDA. 333 



the injection. On post-mortem examination there was 

 found in all cases intense and often hsemorrhagic inflam- 

 mation of the intestinal mucous membrane. 



Bacillus cavicida (Brieger). 



These organisms present the form of very small rods Brieger's 

 about twice as long as broad ; they were isolated by !acnu~ Plg 

 Brieger* from human faeces. They form colonies on 

 nutrient jelly composed of irregular concentric rings ; 

 the cultivations present an appearance resembling that 

 of the scales on the back of a tortoise. On potatoes 

 they form, pretty quickly, dirty yellow masses. Guinea- 

 pigs are killed without exception within 72 hours by the 

 subcutaneous inoculation of the most minute quantities 

 of the cultivation; rabbits and mice are for the most 

 part immune ; if guinea-pigs are fed with the cultivation 

 no bad result follows. Kochf has stated that the guinea- 

 pigs killed by subcutaneous injection show alterations 

 in the small intestine, marked injection of the mucous 

 membrane, and a large quantity of thin fluid contents ; in 

 short, similar symptoms to those formerly obtained by 

 the subcutaneous injection of mixtures of bacteria. 



Bacillus coprogenus parvus (Bienstock). 



This is an extremely small slowly-growing bacillus, Bienstock's 

 obtained by Bienstock on several occasions from human 

 fasces. They are only slightly longer than broad, so 

 that it is only under high powers that the rod form can 

 be distinctly seen ; they grow very slowly on nutrient 

 jelly; in the course of weeks the cultivation extends 

 from the line of inoculation to a distance of scarcely 

 1 mm., and forms a scarcely visible layer on the nutrient 

 soil. If white mice are inoculated with a cultivation 

 marked O3dema occurs in the neighbourhood of the 

 seat of inoculation within 10 hours ; the animals die 

 24 hours later ; after death the bacilli can be dernon- 



* Zeitschr.f. physiol. Chem., vol. viii., p. 308. 



f Conferenz zur Erorterung der Cholerafrage, 2 Jahr. 



