338 BACILLUS PATHOGENIC IN ANIMALS. 



proof, however, does not appear to have been furnished ; 

 Occurrence of in Koch's laboratory, as well as in the author's, u 



the same , 



bacilli in the bacillus has been repeatedly isolated from the intestinal 

 teatine. contents of man and animals which is absolutely identical 



with that described by Emmerich both as regards micro- 

 scopical characters, growth in cultivations, and patho- 

 genic action. (The bacterium coli commune obtained 

 by Escherich from the intestinal contents shows accord- 

 ing to the description only very unimportant differences, 

 due probably to differences in the nutrient substratum, 

 and it is possibly identical with the bacillus of which 

 we are speaking.) Hence there is no ground for the 

 assumption that Emmerich's bacilli play any etiological 

 role in the cholera process ; on the contrary, they repre- 

 sent a species of bacterium which occurs frequently in 

 the intestine, and which corresponds in its pathogenic 

 action on animals with other intestinal bacteria. 



Bacillus necrophorus (Loeffler). 



Loeffler's This organism was obtained by Loeffler,* by the 



cause necrotic inoculation of small particles of broad condylomata into 

 processes. the an t e rior chamber of the eye of rabbits. The bacilli 

 are of varying length, but of uniform thickness, and 

 they often form long thin threads, with a slightly wavy 

 Cultivation outline. They do not grow on the ordinary nutrient 

 experiments . me fa &} on ]y slightly in horses' serum and in chicken 

 broth, and best in neutralised rabbit broth. A whitish 

 down is formed after about 3 days around the pieces of 

 the organs which are placed in the rabbit broth, so that 

 the particles of tissue appear as if they were enveloped 

 in cotton wool ; after a few days numerous white flakes 

 are seen floating in the fluid consisting exclusively of a 

 dense network of these bacilli, which have grown in the 

 form of long threads. Here and there swellings are 

 found in the threads which may be looked on as involu- 

 tion forms, and there are in addition light stained spots,* 

 which, however, do not, on the whole, give the impres- 

 inoculationon sion of spores. If rabbits are inoculated on the ear, or 



* J/trtA. a. d. Kaiserl Ges. Ami., vol. ii., p. 493. 



