DEVELOPMENT OF LIVING MATTEE. 



49 



In the thin layer of cartilage of a dog, eight to ten years 

 old, the compact shining substance is relatively scarce, and, as 

 a rule, traversed by vacuoles. Most of the cartilage-cavities con- 

 tain a pale granular protoplasm and vesicular nuclei with dark 



contours, and a varying 



^^SSHSte number of nucleoli. (See 



?||, Fig. 16.) 



These features were 

 H found in the middle re- 



j| ! gion, between the articu- 



lar surface and the border 

 of the epiphyseal bone. In 

 / ^ ' ' - young animals, the yellow 

 mjBjil substance, on an average, 



occurs the more the nearer 

 to the bone the examina- 

 tion is made. Immediately 

 FIG. 16. CARTILAGE-CORPUSCLES FROM A on the border of the bone 

 SAGITTAL SECTION OF THE CONDYLE OF 

 THE FEMUR OF A DOG, EIGHT TO TEN 

 YEARS OLD. 





A, corpuscle with several gray lumps besides the 

 vesicular nucleus ; _B, corpuscle with an hour-glass- 

 shaped nucleus ; C, corpuscle with an oblong central 

 nucleus. Magnified 800 diameters. 



the centers of the large 

 cartilage-cavities, which 

 are inclosed by a calcined 



. 

 baSlS-SUDStance, are OCCU- 



T ^ pr q "hvloyo-p Tnapi of thp 

 P 16CL D J lar g e maSS( 



yellow substance, which 

 in this situation is supplied with numerous vacuoles, and with 

 lower powers appears coarsely granular. Each central lump is 

 surrounded by a zone of a pale, finely granular or structureless 

 substance, which is separated by a light, narrow rim from the 



FIG. 17. BONE-CORPUSCLES FROM A LONGITUDINAL SECTION OF THE 

 THIGH-BONE OF A PUP, FIVE DAYS OLD. 



-P, corpuscle with a vacuoled shining nucleus; B, basis-substance. Magnified 800 

 diameters. 



4 



