100 



ORIGIN OF COLORED BLOOD-CORPUSCLES. 



ent shapes were present, which had the appearance of having 

 originated by the splitting up of larger lumps. (See Fig. 27.) 



As the shining, solid corpuscles exhibited stages of develop- 

 ment advanced to the formation of nearly perfect red blood- 

 corpuscles, I considered them as juvenile forms of the latter, and 

 proposed for their designation the term " haematoblasts." I 



concluded that a 

 part of the carti- 

 lage-corpuscles, or 

 a portion of the 

 body of such a 

 corpuscle, had be- 

 come transformed 

 into haematoblasts. 

 Formation of 

 Blood in Inflamed 

 Bone. In speci- 

 mens obtained 



FIG. 28. BONE-CORPUSCLES FROM THE COMPACT fr P a d .^ s tlbia > 



PQRTION OF A DOG'S TIBIA, INJURED WITH A which, eight days 



RED-HOT IRON, EIGHTH DAY OF INFLAMMATION, before the death of 



CHROMIC ACID SPECIMEN. [PUBLISHED IN 1872.] the animal, was 



The number ol blood-corpuscles varies in A, B, C. Magnified pUTDOSely iniured 

 800 diameters. -. -, , . 



with a red-hot iron, 



without opening the central medullary space, I found in the 

 bone-tissue numerous cavities, which, besides a finely granular 

 protoplasm, contained red blood-corpuscles. (See Fig. 28.) 



The suspicion arose that the blood-corpuscles had formed 

 from the bone-corpuscles, which might be confirmed by finding 

 stages of transition. 



Such stages were really discovered in many of the specimens. 

 I met in the cavities of the bone-tissue with manifold formations 

 of a substance the characteristics of which were : absence of a 

 visible structure, a high degree of luster, and a yellow color. 

 This substance appeared either in the shape of ledges bordering 

 the pale, granular protoplasm, or of lumps with fine scallops or 

 of glistening disks, and lastly, of corpuscles looking like red 

 blood-corpuscles with the central cup-shaped depression, and, 

 in side-view, biscuit- shaped. Lumps of this substance may some- 

 times be composed of coarse granules. (See Fig. 29.) 



Identical formations were also found in blood-vessels. We 

 are justified in calling corpuscles that we find within blood- 

 vessels, blood-corpuscles of some kind. Now, as these corpuscles 



