366 INFLAMMATION. 



contained granules and lumps of a blackish-brown color, which 

 were most numerous at a certain distance away from the border 

 of the wound. Extremely minute black granules also were found 

 in the basis-substance. That these granules were animal char- 

 coal could easily be determined by comparing them with the 

 charred pastids attached to the surface of the wound, and with 

 the eschar of the cartilage of other animals. But how did the 

 charred granules penetrate the cartilage corpuscles ? There must 

 have been either a carboiiification of certain parts of the cor- 

 puscle and the basis-substance, or else the coal particles had 

 been transported from the surface of the wound toward the 

 periphery. 



The supposition of a partial carbonification was not sustained 

 by experiments on other animals, cats and rabbits, and I 

 never succeeded in producing brown granules in the corpuscles 

 situated in the neighborhood of the burnt place of live or dead 

 cartilage. The conclusion, therefore, became admissible that the 

 coal particles realty were transmitted within the basis-substance by 

 an active process of the cartilage corpuscles and their offshoots. 



Other experiments with powdered vegetable carbon and cin- 

 nabar, forced into fresh wounds of the cartilage, did not yield 

 satisfactory results. I succeeded but once in demonstrating the 

 presence of cinnabar granules in a cartilage corpuscle inclosed 

 by an uninjured basis-substance. Cinnabar granules, on the 

 contrary, which I had injected into the jugular vein, I invariably 

 succeeded in finding in the cartilage corpuscles, within the dis- 

 trict of inflammation, both in inflammatory corpuscles, filling the 

 enlarged cartilage cavities, and also in cartilage corpuscles, 

 apparently unchanged. I can, therefore, corroborate the asser- 

 tions made by Reitz and Hutob. 



In inflamed cartilage I have often seen red blood-corpuscles arising from 

 both the corpuscles of cartilage and medulla. The insular and intravascular 

 formation of red blood-corpuscles in some cases proved to be extremely 

 active. After injuries inflicted on the lateral surface of the condyles, I 

 observed enlarged fusiform cavities, which evidently had sprung from carti- 

 lage, partly or totally filled with initial forms of red blood-corpuscles the 

 " haBmotoblasts " as well as with fully developed corpuscles. Solid bioplas- 

 son tracts sometimes directly connected the closed cavities of the above 

 description, which were found in a large number, especially toward the ten- 

 don-tissue ; they were sometimes hollow, and contained a single chain of red 

 blood-corpuscles. The process of new formation of blood-vessels and blood 

 proved to be identical with that noticed in inflamed bone-tissue, and for fur- 

 ther particulars I refer to the article on inflammation of bone. 



