370 



INFLAMMA TION. 



with lime-salts. In this way are originated new trabeculae, with 

 a high degree of luster, between which, in irregularly arranged 

 cavities, in part nucleated bioplasson bodies are left. In the 

 reealcified basis-substance we can trace the former medullary 

 corpuscles, as their general configuration is unaltered. The 

 reticular structure of this basis-substance is distinctly visible 

 without any re-agent, owing to the high degree of refraction of 

 the fields, infiltrated with lime-salts. (See Fig. 157.) 



The second series of changes concerns the bioplasson itself : 

 it returns in a relatively short time from the phase of advanced 



FIG. 156. TRANSFORMATION OF COMPACT BONE INTO MEDULLARY TISSUED 

 TIBIA OF A DOG, EIGHTH DAY OF INFLAMMATION. CHROMIC Aero 

 SPECIMEN. 



H, widened Haversian canal ; C, projections of the compact bone, with considerably 

 enlarged and apparently augmented bone-corpuscles; J, islands of bone; M, medullary tissue 

 containing newly formed blood-vessels. Magnified 300 diameters. 



development into the juvenile condition. This occurs before any 

 other change, and is quite constantly observed in the homogene- 

 ous nucleus of plastids in the younger, and the nucleolus of 

 those in older animals. The nucleus is transformed into a bright, 

 yellowish body, which divides into several lumps. In the in- 

 flamed district, beginning from the second and third day of 

 inflammation, we meet with bone-corpuscles, containing divided 

 nuclei, even in unchanged osseous lamellae 



