INFLAMMA TION. 



371 



Rejuvenescence may involve either the larger portion of 

 bone-corpuscles or the whole corpuscle, and these bodies are 

 partially or totally transformed into yellowish, shining lumps, 

 which I formerly considered hsematoblastic (see page 101). The 

 dissolution of the basis-substance around the homogeneous lump 

 takes place in the same manner, as described above. 



The return to the juvenile condition, however, may at a com- 

 paratively early date invade not only the central bone-corpuscle, but 

 also take place, to a greater or less 

 extent, in the bioplasson, inclosed in 



the basis-substance. Some offshoots j_ _ 



of the bone-corpuscle may become |^%fl 



broader; in some of them even ^^^lf^fe\^& 



rejuvenescence may occur, inde- 

 prudently of the central bioplas- 

 son body. Lastly, this change 

 may affect the whole mass of bio- 

 plasson present in a territory, as 

 illustrated by Fig. 40, page 126. 

 Here the retrogressive change in 

 the bioplasson preceded the disso- 

 lution of the basis-substance. 



The result of the recurrence to 

 the juvenile stage of development 

 is different, according to its degree. 

 A number of bright, homogeneous 

 lumps may arise from the bioplas- 

 son of the bone-corpuscle, as well 

 as from that of the basis-substance, 

 and each lump, even the most mi- 

 nute, is enabled to produce a new 

 element. This new formation, 

 traceable step by step in the me- 

 dullary spaces, is due to the differentiation of compact bioplasson 

 into a reticulum, therefore an advance toward a higher stage. 

 Each lump, or each element, under these circumstances, remains, 

 by means of delicate filaments, in living connection with all its 

 neighbors. (See Fig. 158.) 



Should the division of young bioplasson into small lumps 

 occur at a very early stage, and very rapidly, the formations 

 which I have termed " haematoblasts " will be the result. Each 

 haematoblast, by being severed from the neighboring elements. 



FIG. 157. KECALCIFICATION OF 

 THE MEDULLARY TISSUE OF A 

 DOG'S TIBIA, INJURED WITH 

 BED-HOT IRON, EIGHTH DAY 

 OF INFLAMMATION. CHROMIC 

 ACID SPECIMEN. [PUBLISHED 

 IN 1873.] 



P, large, nucleated bioplasson bodies ; 

 .B, calcified basis-substance, exhibiting a 

 distinct reticular structure. Magnified 

 800 diameters. 



