INFLAMMATION. 381 



"but it is living matter exclusively which is enabled to reproduce 

 its kind, and therefore capable of producing the extensive new 

 formations which give rise to new tissues, such as pseudo-mem- 

 branes, callosities, vegetations, etc. 



It is not the cell and not the living portion of the cell which 

 alone grows and proliferates j in the tissue, everything that is 

 endowed with life can do so, consequently that portion of living 

 matter which is inclosed by basis-substance also grows and pro- 

 liferates. To this extent, made clear by observations and infer- 

 ences, as far as connective tissue is concerned, we return to the 

 stand-point of Eokitansky, inasmuch as we admit that the so- 

 called " intercellular substances" are endowed with the capacity 

 of growth. 



There is no reason, however, to speak hereafter of a humoral 

 or solidar pathology, any more than of a cellular pathology. There 

 exists but one pathology, and that is the pathology of living matter. 

 That only which is alive can become the subject of disease. 



THE HEALING PROCESS OF FRACTURED BONES. 



In several of m'y publications, issued in 1873, and quoted in 

 the foregoing articles, incidental references are made to the 

 phenomena of the healing process in fractured bones, which I 

 propose here to include in one article. Later writers on this 

 subject* have advanced no new views, as they have not con- 

 sidered the inflammatory process in the light of the bioplasson 

 theory. 



My researches were made in the leg-bones of dogs, cats, and 

 rabbits, which I fractured designedly while the animals were 

 kept under anaesthesia. In all instances I produced a displace- 

 ment of the broken ends, in order to induce a somewhat higher 

 degree of inflammation the covering skin always remaining 

 intact. How the healing process of fractured bones progresses 

 by primary intention i. e., when the broken ends are in close 

 contact, is not known. All the numerous observations and con- 

 clusions concerning healing by primary intention in the soft 

 tissues require revision, as a thorough understanding of this 

 process is possible only through a knowledge of the minute 

 structure of the tissues involved. None of the authors have had 



* J. Hofmokl, "Ueber Callusbildung." Wiener Mediz. Jahrbiicher, 1874. 

 Here an exhaustive account of the literature on this subject is found. 



