INFLA MM A TION. 



387 



process is exactly like that of the normal dissolution of carti- 

 lage, which leads to the new formation of medullary tissue, and 

 subsequently of bone. 



Meanwhile, at the fractured surfaces of the bone, similar 

 medullary spaces have formed in consequence of the dissolution 

 of the basis-substance of the bone and an increase of its bioplas- 

 son material. The connection of the irregular, bay-like medul- 

 lary spaces of the bone with those of the adjacent calcined 

 cartilage can be traced directly. 



From the medullary tissue, which is the offspring of the 



FIG. 163. CARTILAGINOUS CALLUS, EIGHTEEN DAYS AFTER THE SUBCU- 

 TANEOUS FRACTURE OF THE TIBIA OF A CAT. CHROMIC ACID SPECIMEN. 

 [PUBLISHED IN 1873.] 



C', cartilage corpuscles in a striated basis-substance; M, elongated medullary plastids, 

 tending toward the formation of basis-substance, or resulting from a dissolution of basis-sub- 

 stance ; -B', Ift, club-like spaces, lined by a continuous bioplasson layer, containing haemato- 

 blasts and red blood-corpuscles. Magnified 800 diameters. 



inflamed periosteum, bone-tissue arises, in exactly the same man- 

 ner as in the normal development of bone (see page 247). This 

 bone-tissue establishes the formation termed definitive callus (Du- 

 puytren). 



The trabeculae of bone in children and animals begin to 

 appear in the fourth week after the fracture ; these at first are 



r 



