388 



INFLAMMA TION. 



very irregular formations, exhibiting an indistinctly striated, cal- 

 cined basis-substance and very large and irregular bone-corpus- 

 cles. The medullary spaces are filled with medullary corpuscles, 

 and contain, in their centers, newly formed blood-vessels, which 

 are smaller the nearer they approach the compact structure of 



FIG. 164. EXOSTOSIS AFTER PERIOSTITIS OF THE TIBIA OF A DOG IN THE 

 FIFTH WEEK OF INFLAMMATION; IDENTICAL IN STRUCTURE WITH THE 

 DEFINITIVE CALLUS. CHROMIC ACID SPECIMEN. 



C, superficial compact layer, with H8, the Haversian systems, and SS, newly formed 

 medullary spaces ; H, vascular canals, widened into medullary spaces, S ; T, trabeculae of 

 newly formed bone, with large and irregular bone-corpuscles, inclosing large medullary 

 spaces, MS. Magnified 200 diameters. 



the injured bone. Unquestionably, also, the injured muscle-tis- 

 sue shares in the formation of both the provisional and the defin- 

 itive callus, always through the intermediate stages of medullary 



