INFLAMMATION. 



393 



lacunas in which the bioplasson body, with its net-work, was yet distinguish- 

 able, especially where the sequestrum had been attached to the periosteum, 

 I found, also, in the preparation from the upper jaw, some comparatively 

 unchanged bone-corpuscles."* But the majority of the bone-corpuscles, and 

 especially in the neighborhood of the Haversian canals, were either empty or 

 their bioplasson bodies were shriveled up (probably the remains of the living 

 matter), only showing a few coarse granules. (See Fig. 166.) No signs of 

 fatty degeneration could be seen, for 

 the granules were stained violet by 

 chloride of gold. Many lacunse 

 showed no structure at all, the con- 

 tents looking rather like a mass of 

 coagulated albumen. In none of these 

 lacunae was the characteristic struct- 

 ure of bioplasson recognizable. 



To sum up my observations, I 

 found : 



First. The lacuna? contain a bioplas- 

 son body, with a distinctly visible net- 

 like arrangement, to be regarded as the 

 living matter proper. 



Second. The basis -substance is 

 pierced by numerous coarse and fine 

 canaliculi, communicating with each 



FIG. 166. NECROTIC BONE-TISSUE OP 

 THE LOWER JAW OF A WOMAN, AGED 

 THIRTY-EIGHT YEARS. CHROMIC 

 ACID SPECIMEN, STAINED WITH 

 CHLORIDE OF GOLD. 



oilier, as well as with the lacunae. 



Third. The bioplasson bodies, which 

 do not quite fill the lacunce, send off- 

 shoots of the living substance into the 

 canaliculi, but can only be seen in the 

 coarser ones. 



Fourth. In necrotic bone, traces of 

 former osteitis are visible, but no blood-vessels present in the Haversian canals? 

 which are filled with micrococci. 



Fifth. In necrotic bone, most of the lacuna! contain no bioplasson, but either a 

 coarsely granular or a structureless mass remnants of the living matter and 

 coagulated albumen. 



Three lacunae : LI, with two clusters of a 

 granular mass; L*, with scanty granules ; LS, 

 with a nearly homogeneous mass. Magnified 

 1000 diameters. 



RACHITIS AND OSTEOMALACIA. 



During the years of 1872 and 1873, I made a number of 

 experiments, for the purpose of elucidating the causes of rachitis 

 and osteomalacia. The results of these tedious and expensive 

 experiments I published in 1873, in the form of a provisional 

 communication.t 



* An important feature is not mentioned in this article viz. : that even in apparently 

 unchanged bone-corpuscles the nuclei were jagged, as if shriveled, this sufficiently indicating 

 death of bioplasson. ED. 



t Anzeiger der Akademie d. Wissensch. in Wien, 19 Juni, 1873 ; und Vortrag in der Ge- 

 sellschaft d. Aerzte in Wien, October, 1873. 



