INFLAMMATION. 401 



and pigment clusters, but no colloid corpuscles. The resem- 

 blance the case bore to the second case of malacic ribs was very 

 striking. 



In conclusion, I wish to say a few words as to the withholding of lime 

 food in the animals experimented upon. It was, in fact, only a reduction, 

 but not by any means an entire cutting off of the lime supply. The dogs and 

 cats were fed with fresh boiled meat, with fat, with milk and white bread ; 

 but no bones were given. The desire of all these animals for lime food, 

 during the treatment with lactic acid, was evident. The cats and dogs rushed 

 for egg-shells, whenever they came within their reach ; the squirrel scraped off 

 the kalsomining from the wall so eagerly that its cage had to be removed 

 from the wall, though its food was that suitable for squirrels. 



In a dog, in which osteomalacia had been induced, I produced a subcuta- 

 neous fracture of the leg-bones. When the animal was killed, seven weeks 

 after the fracture, the callus exhibited a marked cartilaginous new formation, 

 but with only a scanty deposition of lime-salts and very limited new formation 

 of bone near the injured bone-tissue. As in the above-named period the 

 fractured bones of normal dogs invariably exhibited the formation of a 

 defined cancellous bone-callus, in the dog treated with lactic acid the forma- 

 tion of a bone-callus was obviously prevented. 



As to the case of the seven months fostus, completely destitute of bones, 

 born of a woman who for months during her pregnancy had fed the animals with 

 lactic acid, I wish to state that this woman must certainly have inhaled the 

 vapors of lactic acid, more particularly if poured into the warm soup destined 

 for the animals. The woman was otherwise healthy, and remained so after 

 delivery ; nevertheless, it must be mentioned that, several years previously, 

 she had given birth to a child which in early childhood was slightly rachitic. 

 The seven months foetus died of cerebral hemorrhage, which had evidently 

 taken place during delivery, as the protecting skull-bones were absent. 



2. INFLAMMATION OF MUSCLE. TRICHINOSIS. 



t 



In 1868,* I published a series of observations and experiments 

 leading to the conclusion that the villi of the small intestine had, 

 at their points, perforations which opened directly into the cen- 

 tral lymph-vessel of the villus. The existence of these openings 

 could not, however, be positively proved. If these were really an 

 anatomical condition, we could easily understand how the embryo 

 trichinae are transported from the cavity of the small intestine, 

 first into the chylif erous duct and afterward into the vascular 

 system. The trichinae could be carried with the blood, and fixed 



* "Zur Kenntniss der Diinndarmzotten." Sitzungsber. d. Wiener Aka- 

 demie d. Wissensch., Iviii., Bd. 1868. 



26 



