402 INFLAMMATION. 



as emboli in the tissue of striped muscles, at the points where the 

 arteries merge into capillaries, which, owing to their rectangular 

 division (see page 274, fig. 117), would retain the worms. Muscles 

 which have a continuous motion and a markedly rectangular 

 division of their blood-vessels f. i., the diaphragm would be 

 the first to be invaded by the parasites, while muscles without 

 this rectangular arrangement of the vessels f. i., the heart 

 would not be apt to become trichinosed. 



The theory that the trichina embryos perforate the walls of 

 the intestine, and thence migrate into the muscles, is highly 

 improbable, as these parasites have no apparatus for perforating 

 tissues. 



At the time before mentioned, I made in the Vienna Veterinary 

 School a number of experiments for the purpose of observing 

 trichinae in the chyliferous system of the intestine. I fed Guinea 

 pigs with fresh trichinosed muscle ; but these experiments proved 

 to be failures, as the animals became so rapidly affected after a 

 few days that all of them died, and I looked in vain for embryonal 

 trichinae in the villosities of their small intestines. 



As soon as the embryos of trichinae reach the muscle an 

 inflammation of this tissue (myosibis) sets in, which I have studied 

 in all its phases. 



As to inflammatory changes of smooth muscle, we know,, 

 through the researches of Durante and others, that the spindles 

 divide into rows of inflammatory corpuscles, which at first retain 

 the general shape of the original muscle-spindles. Later, the cor- 

 puscles break apart in the same way as those sprung from con- 

 nective tissue. 



Inflammation of the striped muscles has, since 1851, often been 

 the subject of microscopic researches. Some observers have 

 asserted that only the nuclei of the muscle-fibers participate in 

 the inflammatory new formation j others, that both the nuclei and 

 the contractile substance proliferate ; again, others have denied 

 any participation of nuclei or contractile substance, believing that 

 both perish, and that the whole inflammatory new formation is 

 due only to an emigration of colorless blood-corpuscles. Colberg 

 especially, in 1864 asserted that in trichinosed muscles an increase 

 of the nuclei occurs. Spina, one of the recent writers on the 

 inflammation of muscle, based his views upon researches made in 

 the frog's tongue, which he had artificially inflamed; he claims 

 that the nuclei become much augmented, and that the contractile 



