416 



INFLAMMA TION. 



ular bioplasson "bodies of the size of colorless blood-corpuscles, indicating that 

 immigration of such corpuscles had taken place. 



In other portions of the gray substance a marked proliferation of the gang- 

 lionic bodies can be observed. There are bodies with enlarged and beaded 

 nucleoli, bodies with two or three isolated nucleoli, bodies with two or three 

 coarsely granular nuclei, sprung from a division of the original nucleus, as is 

 proved by the presence of facets, where the nuclei lay against one another. 

 (See Fig. 175.) Many ganglionic elements are transformed into coarsely 

 granular, nearly homogeneous, lumps, and split into smaller lumps, varying in 



number from two to seven or eight. 

 The clusters of bioplasson bodies 

 are grouped together in such a way 

 as to retain the general shape of 

 the ganglionic body, considerably 

 enlarged. The offshoots of these 

 elements are in many instances 

 still recognizable as being either 

 enlarged and coarsely granular or 

 broken apart into rows of bioplas- 

 son bodies. 



As to the origin of medullary 

 elements within the ganglionic 

 bodies, I can state positively that 

 they have originated by a process 

 FIG. 175. INFLAMMATORY CHANGES OF of endogenous growth from the 

 THE GANGLIONIC ELEMENTS OF THE bioplasson of the ganglionic bodies 

 GRAY SUBSTANCE OF THE BRAIN. themselves. First, the living mat- 

 ter was increased, hence we explain 

 the coarsely granular and homo- 

 geneous looks of such an element ; 

 next, marks of division had formed 

 by the division of living matter into 

 angular lumps, closely packed to- 

 gether so as to flatten each other, and separated by a thin layer of fluid, which 

 everywhere was traversed by delicate conical offshoots, uninterruptedly con- 

 necting all newly formed lumps with each other. Some of these lumps, 

 apparently, had further advanced in development than others ; while some 

 looked still shining and homogeneous, others were already coarsely granular, 

 and presented a marked formation of a nucleus and a nucleolus. Again, all 

 these formations, granules, nucleolus, and inclosing shells are united by 

 delicate threads. 



Lastly, the whole ganglionic element and its offshoots had broken apart 

 into medullary or indifferent corpuscles, which, so long as they remain united 

 to one another by delicate threads of living matter, represent an indifferent, 

 medullary, or inflammatory tissue, identical with that arisen from the gray and 

 white substance of the brain. If, on the contrary, the uniting offshoots be 

 torn, the isolated medullary elements will produce pus-corpuscles, and an 

 accumulation of such corpuscles gives rise to what is called an abscess. In 

 the pus taken from the abscess of the brain under consideration, besides pus- 

 corpuscles, a large number of bioplasson bodies were found suspended in 

 the fluid, in size considerably exceeding that of ordinary pus-corpuscles. 



6ri, coarse granules and new nuclei in the body 

 of the ganglionic element ; (?*, splitting of the 

 ganglionic element on its peripheral portion ; G 3 , 

 the whole body transformed into medullary ele- 

 ments : A, axis-cylinder exhibiting the same 

 change. Magnified 600 diameters. 



