430 INFLAMMATION. 



slight inflammatory process. The medullary corpuscles, being 

 infiltrated with the colloid material, either remained in irregular 

 groups, or, becoming elongated, gave rise to the concentrically 

 striated corpuscles, in a way similar to that in which the territo- 

 ries of connective tissue are formed. In the center, sometimes 

 an unchanged plastid is seen, or a larger homogeneous mass, or 

 a shallow depression, termed an umbilicus. 



WAXY DEGENERATION OP THE CEREBELLUM. BY J. BAXTER EMERSON.* 



Mr. B. was the youngest of a family of seven children. His mother died of 

 acute encephalitis, terminating in abscess ; a maternal uncle and aunt both 

 showed symptoms of dementia late in life. One of his sisters has suffered for 

 several years with hysteria ; a second sister has at the present time posterior 

 spinal sclerosis. When about fifteen years old, he was thrown from a car- 

 riage, and received a severe scalp wound on the posterior part of his head, 

 from which he seemed to recover. His habits were regular. He was much 

 troubled with naso-pharyngeal catarrh. At the age of twenty-eight he lost all 

 his property, which worried him excessively; soon he found that he was 

 losing flesh and strength, that his appetite was poor and his digestion bad ; he 

 also had the tendency to fall when walking or on turning suddenly. His 

 brother noticed that he became slower in his work. In January, 1874, the 

 above symptoms returned; he began to stammer, and would often forget 

 localities and names. These symptoms were intermittent in character ; at 

 times he was apparently well. In September, 1874, he was married, and, 

 while on his wedding trip, his wife noticed that if he endeavored to walk 

 down a flight of steps, he would become pale and complain of vertigo. Shortly 

 afterward he was attacked with most intense pain in the head, accompanied 

 with great irritability, photophobia, and inability to stand alone. These 

 acute symptoms lasted several days, and for several weeks he had to be led to 

 prevent his falling. About a month later he had a second similar attack, this 

 time losing the power of speech and being " delirious." Later, he complained 

 of "pain in the forehead," numbness of the extremities, occasional twitching 

 of the muscles, and he was unable to walk without assistance. On two occa- 

 sions he asserted that he was blind, which assertion he persisted in for two 

 days. He was exceedingly childish in his actions. Toward the latter part of 

 the summer of 1876, he became violent, his hallucinations and delusions 

 being of an exalted character. 



On October 5, 1876, I found his left pupil dilated, the tongue tremulous, 

 the power of coordinating the muscles much impaired, those of the left side 

 more so than the right ; the left biceps permanently contracted, so as to keep 

 the fore-arm at an angle of about one hundred and thirty-five degrees with the 

 axis of the arm; contractile power of the muscles on the right side more 

 marked than on the left ; an almost incessant movement of either the fore-arm 

 and hand, or grinding of the teeth ; partial anaesthesia of the left side ; 

 aphasia of both varieties, but principally amnesic ; hallucinations and delu- 

 sions of a very exalted character, seeming to dwell principally on financial 



* Abstract of the paper "Peri-encephalitis," by J. Baxter Emerson, M. D., New- York. 

 Journal of Nervous and Mental Disease. Chicago, April, 1880. 



