496 



TUMORS. 



oblong plastids, which are apparently isolated. The more nearly 

 the reticulum approaches to a circular arrangement, and the 

 smaller its composing spindles, the more closely allied is this 

 variety to that of myxo-myeloma. Finally, all distinguishing 



marks are lost, and spindle-net my- 

 eloma and myxo-myeloma blend 

 with each other. (See Fig. 196.) 



The " giant-cell sarcoma" of 

 Virchow cannot be considered as 

 a tumor sui generis, for the so- 

 called " giant-cells v never consti- 

 tute the entire mass of the tumor. 

 They are intermixed with fibrous 



FIG. 194. SPINDLE-MYELOMA, COM- 

 POSED OF LARGE PLASTIDS. FROM 

 THE OMENTUM OF A WOMAN. 



L, nucleated spindles cut longitudinally ; 

 O, spindles cut obliquely ; F, spindles cut 

 transversely. Magnified 600 diameters. 



connective tissue, as well as 

 with fibro-myeloma, and are 

 more numerous and better de- 

 veloped the greater the amount 

 of basis-substance contained in 

 the surrounding tissue. As, in 

 our view, the multinuclear plas- 

 tids arise from a fusion of me- 

 dullary elements, whenever 

 there is a tendency to form ter- 

 ritories, usually of cartilage 

 and bone, it will be understood 

 from this fact that the malignity 

 of these .tumors is very slight. 

 Their favorite site of growth is the periosteum, especially the 

 periosteum of the jaw-bones (so-called lt epulis "), and a perma- 

 nent cure will ensue if the tumor is thoroughly extirpated. I 

 have examined several globo- and spindle-myelomata which had 

 grown from the maxillary bones, where very little basis-substance 



FIG. 195. SPINDLE - MYELOMA, 

 COMPOSED OF SMALL PLASTIDS. 

 FROM THE CHOROID OF AN 

 ADULT. 



L, nucleated spindles cut longitudin- 

 ally ; O, spindles cut obliquely ; P, pig- 

 ment clusters from theformerpigmented 

 endothelium of the retina. Magnified 

 600 diameters. 



