542 



TUMORS. 



formations in a stage of indifference, furnishing the material for specific 

 formations. 



Now, what is the source of these bodies ? We observe that they appear first 

 in rhomboidal fields, corresponding with the territories of connective tissue. 

 At first one or two lumps only are visible in a territory ; later the whole terri- 

 tory is transformed into a coarsely granular bioplasson mass, which contains 

 a varying number of globular formations. In a still more advanced stage the 

 territory is composed of polygonal plastids. Sometimes we see the connective 

 tissue between two alveoli filled with flat elements, some of which contain 

 large nucleoli. In such places it is apparent that a morphological difference 



FIG. 226. CANCER OF THE SKIN OF THE PAROTID KEGION. 



C, connective tissue ; HE, epithelia, either arranged in closed alveoli or lying in the 

 interalveolar connective tissue. Magnified 600 diameters. 



does not exist between the elements occupying the alveoli and those which 

 lie without much regularity in the neighboring connective tissue. (See Fig. 

 226.) 



In specimens from a so-called flat cancer of the skin of the face, I observed 

 that the connective tissue of the papillae in some places was almost completely 

 transformed into elements having the appearance of epithelia, and to such 



