THE LIVER. 



697 



PV 



B 



formation of pus, the connection of the single bioplasson bodies is lost. Here 

 isolated pus-corpuscles are suspended in the albuminous serum, which latter, 

 in chromic acid specimens such as I have exclusively used for examination, 

 looks finely granular. The epithelia within the lobules of the liver at the 

 same time share in the inflammatory process in a very marked way. Firstly, 

 they swell up ; the cement-substance becomes invisible between a number 

 of epithelia, which now look like 

 large, irregular clusters. The 

 epithelia and the bioplasson 

 bodies arising therefrom be- 

 come coarsely granular, with 

 their living matter augmented 

 to such an extent that the nu- 

 clei are mostly concealed ; they 

 have in part also become in- 

 creased in size, shining, and 

 homogeneous. Many of the 

 granules assume the shape of 

 nuclei, and throughout the 

 whole cluster new lines of de- 

 markation appear, which lead 

 to the formation of compara- 

 tively small bioplasson bodies, 

 viz., inflammatory elements. 

 All these elements are first di- 

 rectly connected with each 

 other by delicate threads, and 

 in this condition represent an 

 indifferent tissue, closely re- 

 sembling that formed from the 

 connective tissue. Lastly, how- 

 ever, they are completely sep- 

 arated from each other and 

 represent pus-corpuscles. (See 

 Fig. 311.) 



The transformation into pus 

 may be localized in the inter- 

 stitial connective tissue alone ; 

 or it may involve the interstitial 

 connective tissue and a portion 

 of the neighboring lobules ; or 

 lastly, a large territory of the 

 liver-tissue, being engaged in 

 the inflammatory process, 

 breaks down into pus. There- 

 suit under all circumstances 

 will be an abscess, varying only in size. As to the emigration of colorless 

 blood-corpuscles, which was thought to be the only source of pus ( J. Cohn- 

 heim), I have nothing to say. The origin of pus, in my specimens at least, 

 could be satisfactorily traced from the breaking down of the tissue itself, so 

 much so, that in my opinion the emigrated colorless blood-corpuscles, if 



FIG. 310. DIAGRAM OF THE FORMATION 

 OF Pus IN THE INTERSTITIAL CONNECT- 

 IVE TISSUE OF THE LIVER. 



PV, portal veiu ; B, bile-duct ; C, fibrous connect- 

 ive tissue; H, cluster of inflammatory corpuscles, 

 sprung from epithelia of a bile-duct ; I, homogeneous 

 lumps, first appearing in the connective tissue ; MC, 

 medullary corpuscles, interconnected ; PC, pus- 

 corpuscles. 



