THE LIVER. 



699 



MC 



mass I met with scanty capillary blood-vessels, and a large number of islands 

 of unchanged liver epithelia, which latter had escaped the transformation 

 into medullary corpuscles and became involved in the newly formed connect- 

 ive tissue. (See Fig. 312.) 



The conclusions I have arrived at are as follows : 



1. The inflammation invariably starts in the interstitial connective tissue of the 

 liver, and secondarily involves a 



varying amount and number of 

 the lobules of the liver. 



2. Both the connective tissue 

 with its blood-vessels and the epi- 

 thelia of the lobules, through an 

 increase of the living matter, be- 

 come transformed into embryo )ia1 

 or medullary elements, thus con- 

 stituting what is termed the in- 

 flammatory infiltration. 



3. The medullary elements orig- 

 inally connected with each other 

 by means of delicate thorns in 

 turn become isolated by rupture 

 of these thorns, and now, being 

 suspended in a serous fluid, rep- 

 resent pus-corpuscles, the sum 

 total of which is called an abscess. 



4. The pus-corpuscles, there- 

 fore, are a direct offspring of the 

 liver-tissue, both connective and 

 epithelial, and no indication could B 

 be seen of an emigration of color- 

 less blood-corpuscles. 



5. On the boundary of the ab- 

 scess the inflammatory tissue is 

 transformed into a homogeneous 

 or striated connective tissue, 

 building a wall around the abscess. 

 In the formation of this also the 

 lU'ritoncitm Chares, if the abscess 

 h ax formed near it. 



LE 



FIG. 312. DIAGRAM OF THE FORMA- 

 TION OF A CONNECTIVE-TISSUE CAPSULE 

 AROUND AN ABSCESS OF THE LlVER. 



MC, medullary corpuscles, arisen from both tin- 

 epithelia of the lobule and the interstitial connect- 

 ive tissue ; 8, medullary corpuscles, spindle-shaped, 

 partly transformed into basis-substance, ; LE, 

 island of unchanged liver epithelia. 



In the foregoing article 

 reference is made to the 

 probability of embolism of 

 pus-corpuscles in the portal 

 veins, causing pyseinic ab- 

 scess of the liver. This is in accordance with the older views held 

 by Cruveilhier, Piorry, Schuh, and others, while Virchow denied 

 the possibility of such an occurrence. 



In microscopic examination of the liver of a man who, after 



