766 



THE U BINARY TRACT. 



interstitial tissue is sparsely traversed by unchanged fibers, but mainly con- 

 verted into a granulated mass, in which only globular, shining, or coarsely 

 granular nuclear bodies, but no isolated elements, are recognizable. The 

 membrana propria is still partly preserved, and we thus ascertain that the 

 epithelium of the tubules has broken up into bodies resembling in every par- 

 ticular those of the connective tissue. 



While some suppurative foci are composed principally of homogeneous 

 lumps, which cannot be considered as completed pus-corpuscles, other foci 

 are made up of coarsely granular bioplasson, in which, at nearly equal inter- 

 vals, nuclei are imbedded. In neither of these cases has a disintegration of 

 the tissue into pus-corpuscles taken place. Foci, on the contrary, which con- 

 tain fluid pus, already recognizable by the naked eye, under the microscope 

 also present nothing but aggregations of isolated pus-corpuscles. The loops 

 of the tufts also take part in the production of pus, inasmuch as the walls of 



FIG. 346. SUPPURATIVE NEPHRITIS. 



T, remnants of uriniferous tubules, whose epithelia are coalesced into multiuuclear 

 masses; their boundary line in part destroyed by the inflammatory infiltration; I, intersti- 

 tial tissue, almost completely converted into inflammatory corpuscles ; all blood-vessels 

 destroyed. The breaking-up into single pus-corpuscles not yet accomplished. Magnified 500 

 diameters. 



the vessels at first split into shining lumps and subsequently into pus- 

 corpuscles. 



The course of suppuration is, therefore, the following : In the first place, 

 it is clear that interstitial tissue, as well as epithelium, can be converted into 

 pus ; the living matter of either of these tissues may return to the juvenile 

 state, the granules becoming enlarged, homogeneous, and shining. We notice 

 groups of such lumps scattered throughout the interstitial and the epithelial 

 tissue. (See Fig. 347.) 



