THE UEINAEY TRACT. 



-767 



Next, with an increasing number of these lumps, the tissue in toto appears 

 converted into a conglomerate of shining lumps, and finally, a differentiation 

 into nucleated corpuscles takes place, representing a stage in which the former 

 tissue is still a tissue, though markedly altered. Only when the continuous 

 mass is torn into separate, nucleated lumps have we to deal with finished pus. 

 The tissue is destroyed in its place we have an abscess. 



The endogenous proliferation of living matter takes place in exactly the 

 same manner in connective tissue and in epithelium. The division into single 

 elements is always a secondary process, and can occur in every stage of the 

 proliferation. Homogeneous lumps break up into a number of granules by 

 the formation of new lines of division within the lump. In the beginning 

 every lump and every granule is united to all its neighbors by fine threads. 

 The living connection is retained even after nucleated bodies have formed 

 from the lumps ; the connection is broken after the formation of pus- 

 corpuscles. 



FIG. 347. SUPPURATIVE NEPHRITIS. 



C, uriuiferous tubule, tilled with a cast, in Avhich remnants of nuclei are imbedded ; L r 

 tubular epithelium, in active new formation of living matter, in the early stages of endoge- 

 nous formation of pus-corpuscles ; V, red blood-corpuscles, partly in vessels, partly extrava- 

 sated in the interstitial tissue, which holds a number of coarsely granular corpuscles. Magni- 

 fied 800 diameters. 



CHRONIC INFLAMMATION OF THE KIDNEYS. BY JEANNETTE B. GREENE, M. D.* 



In accordance with the plan pursued in the laboratory of C. Heitzmanii 

 for the last seven years, we divide chronic nephritis into three main varie- 

 ties, namely, the catarrhal, the croupous, and the suppuratlve. All these 

 varieties of nephritis may appear in the acute form also. Chronic catarrhal, 

 and croupous nephritis may be accompanied by acute recurrences of the 

 disease, and in this way give rise to a secondary subacute condition. 



It is unnecessary to say that such terms as " catarrhal" and " croupous" 

 have no special significance ; but, after having been once adopted in our 

 Printed from the author's manuscript. 



