188 F. E. HENDERSON. 



Exp. XII. Dog 11 kg. Prepared as described above, exp. XVII. Maximum ureter- 

 pressure 80 mm. Hg, blood-pressure 128. Injection-pressure of indigo-carmine 91 mm. Hg. 

 1 hrs. later, blue-tinged urine secreted from other kidney. 2 hrs. later, killed. 

 Irregular patchy bluing of the kidney capsule. On section definite radiating wedge- 

 shaped blue areas extending from pelvis to the capsule. Histological examination showed 

 pigment deposits, most abundant in the collecting tubules and in the convoluted tubules. 

 Two or three glomeruli also contained small deposits. In some areas where much 

 pigment occurred within the tubules and in their cells pigment also was present inter - 

 stitially in small quantities in lymphatic spaces and within blood vessels. 



EXP. XVII. Dog 10 kg. Prepared as above. Blood-pressure 120. Ureter-pressure 

 30 mm. Hg. Injection-pressure 40 cm. water = approximately 30 mm. Hg. In 1 hrs. a 

 trace of blue in urine of right kidney. After 2 hrs. killed. Slight bluing of patches of 

 capsule. On section one or two faint blue streaks extending out to the capsule. Histo- 

 logically indigo-carmine in collecting tubules and in a few convoluted tubules only. 



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Cushny. This Journal, xxvn. p. 429. 1901. 



Gottlieb and Magnus. Arch. f. exp. Path. u. Pharm. XLV. p. 248. 1900. 



Lindemann. Ziegler's Beitrage zur path. Anat. xxvu. p. 1. 1905. 



Starling. This Journal, xxiv. p. 317. 1899. 



Protopopow. Arch. f. d. ges. Physiol. LXVI. p. 1. 



Fagge. This Journal, xxvin. p. 304. 1902. 



Loewi. Arch. f. exp. Path. u. Pharm. xxxv. p. 15. 1905. 



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